We found a non-significant association (hazard ratio (HR) = 1.46, P = 0.66) consistent with Pathways Study findings. However, the GERA cohort also included 1,983 prevalent breast cancer patients with biospecimen collection after diagnosis. In this group, the risk allele frequency in breast ...
Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. 仅用于科研。不用于...
Learning Pathways White papers, Ebooks, Webinars Customer Stories Partners Executive Insights Open Source GitHub Sponsors Fund open source developers The ReadME Project GitHub community articles Repositories Topics Trending Collections Enterprise Enterprise platform AI-powered developer platform ...
Learning Pathways White papers, Ebooks, Webinars Customer Stories Partners Open Source GitHub Sponsors Fund open source developers The ReadME Project GitHub community articles Repositories Topics Trending Collections Enterprise Enterprise platform AI-powered developer platform Available add-ons ...
NDUFA12 (NADH:Ubiquinone Oxidoreductase Subunit A12) is a Protein Coding gene. Diseases associated with NDUFA12 include Leigh Syndrome and Leigh Syndrome With Leukodystrophy. Among its related pathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat pro...
Based on density functional theory (DFT) calcula- tions, H2COH has been recognized as a vital intermedi- ate generated from the further hydrogenation of CO and HCOOH, and it could turn into CH3OH through com- peting pathways [26]. Szkaradek et al. [27] recognized the pathway...
Promotes apoptosis by regul ating three pathways, apoptosome up-regulation, LGALS3/galectin- 3 down-regulation and NF-kappa-B inactivation. Regulates the redi stribution of APAF1 into the nucleus after proapoptotic stress. Do wn-regulates the expression of LGALS3 by inhibiting NFKB1 (By si ...
There are five subtypes of DA receptors, which are further classified as D1-like (D1 and D5) and D2-like (D2, D3, and D4) based on their different intracellular G-protein-coupled signaling pathways. Thus, brain DA receptors are reasonable molecular targets for possible therapeutics to ...
Kinetic Analysis of the Divergence of Reaction Pathways in the Chiral Lewis Base Promoted Aldol Additions of Trichlorosilyl Enol Ethers: A Rapid-Injection ... The aldol addition reaction of trichlorosilyl enol ethers and aldehydes with and without chiral Lewis base catalysts has been kinetically analy...
Smads are important intracellular effectors in signaling pathways of the transforming growth factor-beta (TGF-beta) superfamily. Upon activation by TGF-bet... X Lin,M Liang,YY Liang,... - 《Journal of Biological Chemistry》 被引量: 0发表: 2003年 the use of the slim type fluorescent ...