The expression of UCHL3 is elevated in ovarian cancer patients and is associated with an unfavourable prognosis. Genetic ablation of UCHL3 was found to markedly block ovarian cancer cell proliferation, viability and migration both in vitro and in vivo. Mechanistically, luciferase pathway screening ...
Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injury. Redox Biol. 2021;41:101932. Article CAS PubMed PubMed Central Google Scholar Chamberlain KA, ...
1. Strictosamide alleviated the pathological alterations in DSS-induced acute UC mice. 2. Strictosamide relieved the inflammation in DSS-induced acute UC mice. 3. Strictosamide inhibited the inflammatory response in LPS-induced IEC6/HT-29 cells by restricting the NF-κB pathway. Rights and per...
ubiquitin-protease pathway ubiquitin-proteasome system Ubretid UBT breath test UC UCAS Uceris UCH UCHL1 UCL UCP1 UCP2 UCP3 U-curve phenomenon UDA Udana udder UDP UDP glucose-hexose-1-phosphate uridylyltransferase UDPG UDPGal UDPgalactose UDPGlc ...
Share Korean Dream: Pathway to Peace and Freedom - UC Berkeley with your friends. Berkeley Haunted Hike - Ghost Tour at the UC Berkeley Campus and Beyond Berkeley Haunted Hike - Ghost Tour at the UC Berkeley Campus and Beyond Tomorrow at 8:00 PM In front of Bakar Bioi...
In a previous study, we revealed the proapoptotic function of one of the candidate lncRNAs, Ttc3-209, which was found to act via the ceRNA pathway in a mouse model of I/R damage. To further analyze the role and mechanism of apoptosis-related lncRNAs in RGCs, we selected lncRNA uc007...
Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation. 产品留言 标题 联系人 联系电话 内容 验证码 点击换一张 注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!2.如有必要,请您留下您的详细联系方式!
The Th1-related immune system and lipid metabolism appear to play key roles in the response to endocrine therapy and prognosis in HR-positive/HER2-negative breast cancer. Deleterious somatic mutations in the cell cycle and apoptosis pathway and PIK3CA/AKT/mTOR pathway may be relevant for clinical ...
Here, we report that mTORC1 controls the half-life of uridine cytidine kinase 2 (UCK2), the rate-limiting enzyme in the salvage pathway. Specifically, UCK2 is degraded via the CTLH-WDR26 E3 complex during mTORC1 inhibition, which is prevented when mTORC1 is active. We also find that ...
Mechanistically, GIAT4RA was essential for the degradation of chromatin modifier lymphoid-specific helicase (LSH) by counteracting the deubiquintination in proteasome pathway by binding to 227-589 AA of LSH. GIAT4RA interfered with ubiquitin hydrolase Uchl3-mediated interaction and stabilization of ...