酪氨酸激酶抑制剂(tyrosine kinase Inhibitor)序号 目录号 名称 作用 1. ALX-380-091 17-AAG 抑制HSP90关键ATPase、端粒 …zhidao.baidu.com|基于58个网页 2. 酪胺酸激酶抑制剂 酪胺酸激酶抑制剂(tyrosine kinase inhibitor)营养谘询 药物谘询 癌症治疗谘询中心 英文学名 英文商品名 中文商品名 药物介 …www.ls...
产品名称:酪氨酸激酶抑制剂(Tyrosine kinase inhibitor) 英文名称:Tyrosine kinase inhibitor 产品货号:M02479 产品规格:1mL(10mM)|5mg 本产品为酪氨酸激酶抑制剂。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途! CAS号:1021950-26-4 纯度:99.78% ...
本申请涉及抑制,调节和/或调控酪氨酸激酶信号传导的化合物,含有这些化合物的组合物,以及使用这些化合物来治疗哺乳动物中酪氨酸激酶介导的疾病和病症,例如血管生成,癌症,肿瘤生长,动脉粥样硬化,老年黄斑变性,糖尿病性视网膜病,炎性疾病等的方法. The present application relates to inhibit, regulate and / or ...
Tyrosine kinase inhibitor 1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively. ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商,致力于为广大科研、商业实验室的科学研究者提供高品质的产品与技术服务,不断促进...
Product NameTyrosine Kinase Inhibitor CAS649735-46-6 CBNumberCB00131632 MFC19H19FN4O3 MW370.38 MDL NumberMFCD13194684 MOL File649735-46-6.mol MSDS FileSDS Chemical Properties Density1.42 storage temp.Store at -20°C solubilityinsoluble in H2O; ≥18.5 mg/mL in DMSO; ≥3.39 mg/mL in EtOH wi...
Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelogenous leukemia Protein kinases are a large family of homologous pro- teins comprising 2 major subfamilies, the protein ser- ine/threonine kinases and protein tyrosine kin... BJ Druker,NB Lydon - 《Journal ...
The second promising tyrosine kinase inhibitor against MTC,motesanib diphosphate(AMG-706), is a multikinase inhibitor targeting VEGF, platelet-derived growth factor, and Kit receptors, which lead toantiangiogenicand directantitumor activity. In a phase I trial with AMG-706, one patient with MTC exhi...
TYROSINE KINASE-IN-1 CAS号: 705946-27-6 英文名: XL999 英文别名: XL999;XL999;XL 999;Tyrosine kinase-IN-1;Tyrosine kinase inhibitor 1;XL-999(Tyrosine kinase-IN-1);Tyrosine kinase-IN-1, 10 mM in DMSO;(Z)-5-((1-Ethylpiperidin-4-yl)amino)-3-((3-fluorophenyl)(5-methyl-1H-imidazol...
EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet–Fed Mice Mourao, et al., EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice, Diabetes 58 (2009) ... PO Prada,ER Ropelle,...
kinase family members is associated with EMT and drug resistance, inhibition of these proteins also restores drug sensitivity. TKI with alisertib, an AuroraA inhibitor, partly reverses the EMT and improves EGFR-TKIs resistance.272Combining an AuroraB inhibitor with osimertinib can helpfully prevent EMT...