Epilepsy, affecting at least 2% of the population, comprises a group of disorders of the brain characterized by the periodic and unpredictable occurrence of seizures. It is clear that epilepsy is a major public health problem in that those affected experience the periodic and unpredictable occurrence...
Discrete subicular circuits control generalization of hippocampal seizures 2022, Nature Communications Cellular resolution anatomical and molecular atlases for prenatal human brains 2022, Journal of Comparative Neurology Vector trace cells in the subiculum of the hippocampal formation 2021, Nature Neuroscience ...
Central nervous system presentations range from anxiety and restless- ness to seizures, coma, and death (Banks 2014; Rotenberg and Newmark 2003; Rotenberg 2003b). Pediatric manifestations (Table 5.19) may vary from the classic clinical responses due to their unique vulnerabilities (Hilmas et...
While DCX expression persists in adults, particularly in the temporal lobe and neurogenic regions, it is unknown how seizures influence its expression. The aim of the present study was to explore the distribution and characteristics of DCX-expressing cells in surgical and postmortem samples from 40 ...
A neonatal encephalopathy with seizures in standard poodle dogs with a missense mutation in the canine ortholog of ATF2. Neurogenetics 2008; 9: 41–49. 8 Fyfe JC, Al-Tamimi RA, Liu J, Schaffer AA, Agarwala R, Henthorn PS. A novel mitofusin 2 mutation causes canine fetal-onset neuro...
Gpr98 is a G protein-coupled receptor highly expressed in the ventricular zone of the brain. Mutations of the Gpr98 gene in human account for some of the patients who have Usher syndrome and its mutation in mice causes seizures34. Both Pttg1, a homolog of yeast securin proteins, and ...
In epilepsy research, there is a growing interest in the role of the piriform cortex (PC) in the development and maintenance of limbic kindling and other types of limbic epileptogenesis leading to complex partial seizures. Neurophysiological studies on PC or amygdala-PC slice preparations from...
The HSV-infected mice died of encephalitis with seizures and/or paresis after both i.c. and nose inoculation of the HSV strains and the log PFU/LDs0 could be calcu- lated for each strain. By definition, death after nose inoculation was characterized as neuro- invasiveness, since this route...
Risks of occurrence of psy- choses in relation to the types of epilepsies and epileptic seizures. Folia Psychiatry Neurol Jpn 1983;37:221-5.Sengoku A, Yagi K, Seino M, Wada T. Risks of occurrence of psychoses in relation to the types of epilepsies and epileptic seizures. Folia Psychiatr ...
In conclusion we can state that, on the basis of this retrospective single center observation, epilepsy surgery can control seizures in the majority of patients, that most children have deficits in IQ and one or more cognitive domains already before surgery, and that in most domains including beh...