CELL differentiationA membrane protein's functions are significantly associated with its type, so it is crucial to identify the types of membrane proteins. Conventional computational methods for identifying the species of membrane proteins tend to ignore two issues: High-order correlation amo...
Cell-free RNA from liquid biopsies can be analyzed to determine disease tissue of origin. We extend this concept to identify cell types of origin using the Tabula Sapiens transcriptomic cell atlas as well as individual tissue transcriptomic cell atlases in combination with the Human Protein Atlas RN...
Outer membrane proteins (OMPs) play important roles in cell biology. In addition, OMPs are targeted by multiple drugs. The identification of OMPs from geno... M Hayat,A Khan - 《Protein & Peptide Letters》 被引量: 0发表: 2012年 Functional discrimination of membrane proteins using machine lear...
Additionally, we obtained a time-resolved cell membrane interactome map for the receptor in β cells. Therefore, our study provides a new approach that is generalizable to map endogenous cell membrane interactomes for G-protein-coupled receptors to decipher the molecular basis of their cell-type-...
Association of chromatin with lamin proteins at the nuclear periphery has emerged as a potential mechanism to coordinate cell type-specific gene expression and maintain cellular identity via gene silencing. Unlike many histone modifications and chromatin
A Role for Alström Syndrome Protein, Alms1, in Kidney Ciliogenesis and Cellular Quiescence Premature truncation alleles in theALMS1gene are a frequent cause of human Alstrm syndrome. Alstrm syndrome is a rare disorder characterized by early obesi... G Li,R Vega,K Nelms,... - 《Plos Genet...
This type of division is accompanied by the destabilization of hemidesmosomal protein COL17A1 and cell polarity protein aPKCλ and generates terminally differentiating epidermal cells instead of regenerating the hair follicle niche. With the repetition of these atypical divisions, HFSCs detach from the...
b) Eukaryotic cell: In this type of cell, the nucleus is well structured that means nuclear materials are well organised and surrounded by a nuclear membrane. Chromosomes are organised with DNA, histone protein, and other components. From algae to higher flowering plants and from Amoeba to advan...
body. In general, connective tissue consists ofcellsand anextracellular matrix. The extracellular matrix is made up of aground substanceandprotein fibers. So, in a more detailed way, all connective tissue apart frombloodand lymph consists of three main components: cells, ground substance and fibers...
N. Wag31, a homologue of the cell division protein DivIVA, regulates growth, morphology and polar cell wall synthesis in mycobacteria. Microbiology 154, 725–735 (2008). This study shows that Wag31, a homologue of the cell division protein DivIVA, is localized at the cell pole, regulating...