With the increase in DNA and protein sequencedatabases, there is a growing need for more faster and efficient methods to analyze this large amount of data. One of the most commonly used bioinformatics tools today to study DNA and protein sequences is called BLAST. BLAST stands for Basic Local...
There are several primary sequence databases available that are widely used in the field of bioinformatics. The three main primary databases are GenBank at the National Center for Biotechnology Information (NCBI), the DNA Database of Japan (DDBJ), and the European Molecular Biology Laboratory (EMBL...
Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 18, S96–S104 (2002). Article PubMed Google Scholar Stekhoven, D. J. & Buhlmann, P. MissForest-non-parametric missing value imputation for mixed-type data. ...
Bioinformatics 27, 2288–2295 (2011). Article CAS PubMed PubMed Central Google Scholar Géron, A., Werner, J., Wattiez, R., Lebaron, P. & Mattallana-Surget, S. Deciphering the functioning of microbial communities: shedding light on the critical steps in metaproteomics. Front. Microbiol....
Single cell technologies are rapidly generating large amounts of data that enables us to understand biological systems at single-cell resolution. However, joint analysis of datasets generated by independent labs remains challenging due to a lack of consi
Bioinformatics 27, 2288–2295 (2011). Article CAS PubMed PubMed Central Google Scholar Géron, A., Werner, J., Wattiez, R., Lebaron, P. & Mattallana-Surget, S. Deciphering the functioning of microbial communities: shedding light on the critical steps in metaproteomics. Front. Microbiol....
DPANN archaea, including Woesearchaeota, encompass a large fraction of the archaeal diversity, yet their genomic diversity, lifestyle, and role in natural microbiomes remain elusive. With an archaeal assemblage naturally enriched in Woesearchaeota and st
Birney, E. (2004). An Overview of Ensembl. Genome Research, 14(5), 925–928. doi:10.1101/gr.1860604 Choudhuri, S. (2014). Data, Databases, Data Format, Database Search, Data Retrieval Systems, and Genome Browsers. Bioinformatics for Beginners, 77–131. doi:10.1016/b978-0-12-410471-6....
Biological Databases- Types and Importance. A biological database is a large, organized body of persistent data, usually associated with computerized software designed to update, query, and retrieve components of the data stored within the system.
Multiplexed fluorescence in situ hybridization techniques have enabled cell-type identification, linking transcriptional heterogeneity with spatial heterogeneity of cells. However, inaccurate cell segmentation reduces the efficacy of cell-type identifica