Baseline characteristics were analyzed by treatment groups using means (SDs) for continuous variables and counts and percentages for categorical variables. Balance between groups on baseline characteristics was tested using analysis of variance or a Pearson χ2 test, as appropriate. Adverse events, ...
Random effects analysis was performed for all comparisons, using inverse variance and Mantel–Haenszel methods to calculate the weights for continuous and categorical outcomes. This is a more conservative approach, as data were heterogeneous. Our search did not identify any non-randomised studies. Both...
Per-protocol analyses were used to compare the three groups. Intention to treatment and per-protocol analyses were used to compare the three groups. The χ2test was used for categorical variables and the Kruskal–Wallis test was used for differences between groups using IBM SPSS Statistics (Versio...