To address these questions, we investigated renal injury in N-type calcium channel-deficient db/db mice on the diabetes-prone C57BLKS/J background. In addition, we examined the functional role of N-type calcium channel in cultured podocytes. Results (rtablCdcuwooFeonberhewsiemtoiuigCiadgencb...
www.nature.com/scientificreports OPEN received: 23 May 2016 accepted: 24 November 2016 Published: 09 January 2017 Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes Hooi Hooi Ng1,2, Chen Huei Leo1, Darnel Prakoso1,2...
Type 2 diabetesRoux-en-Y gastric bypassSleeve gastrectomyABCDMDRThe utility of available scoring systems for type 2 diabetes (T2D) remission prediction after metabolic surgery has not been defined in a multi-ethnic Asian population like Singapore. We sought to assess the predictive performance of ...
Type 2 diabetes mellitus is a chronic disease whose health outcomes are related to patients and healthcare professionals’ decision-making. The Diabetes Intervention study in the Canary Islands (INDICA study) aims to evaluate the effectiveness and cost-effectiveness of educational interventions supported ...
Type 2 diabetes mellitus is a chronic disease whose health outcomes are related to patients and healthcare professionals’ decision-making. The Diabetes Intervention study in the Canary Islands (INDICA study) aims to evaluate the effectiveness and cost-e
In contrast, only one study mentions that PCSK9 inhibitors decreased LDL-C and mortality rate but increased the risk of diabetes [61]. In that study, they found that PCSK9 (−/−) mice had reduced plasma insulin level and impaired glucose tolerance [61]....
A number of studies have also reported FasL gene polymorphisms associated with autoimmune conditions such as systemic lupus erythematosus in specific human populations, but others have failed to find such associations in patients with Hashimoto's thyroiditis, Graves' disease, Type I diabetes mellitus, ...
Secoiridoid Dimers and Their Biogenetic Precursors from the Fruits of Cornus officinalis with Potential Therapeutic Effects on Type 2 Diabetes. Bioorg. Chem. 2021, 117, 105399. [CrossRef] 33. Kornpointner, C.; Berger, A.; Traxler, F.; Hadžiabdic´, A.; Massar, M.; Matek, J.; ...
A positive test was indicative of autoimmune diabetes development; however, no mice in these studies tested positive for diabetes. Mice were maintained and used in accordance with the University of Iowa Animal Care and Use Committee Guidelines (#6021655, 10 May 2016) or as approved by the ...
Implementation Science (2015) 10:47 DOI 10.1186/s13012-015-0233-1 Implementation Science STUDY PROTOCOL Open Access Effectiveness and cost-effectiveness of knowledge transfer and behavior modification interventions in type 2 diabetes mellitus patients—the INDICA study: a cluster randomized controlled trial...