The present invention relates to a method of testing for genetic susceptibility to type-2 diabetes in a subject that comprises detecting one or more polymorphisms present in the KCNQ1 gene and/or EIF2AK4 gene in a DNA-containing sample collected from the subject. The present invention permit ...
www.nature.com/scientificreports OPEN Circulating long-non coding RNAs as biomarkers of left ventricular diastolic function and remodelling received: 30 June 2016 accepted: 26 October 2016 Published: 22 November 2016 in patients with well-controlled type 2 diabetes D. de Gonzalo-Calvo1,2, F....
Type 2 Diabetes Diagnosis Several blood tests are used to screen for and diagnosis diabetes: glycated hemoglobin (A1C) test. This blood test indicates your average blood sugar level for the past 2 to 3 months. It measures the percentage of blood sugar attached to hemoglobin, the oxygen-carrying...
Schwartz2,3 Raymond R Townsend1 1Nephrology Division, Perelman School of Medicine, University of Pennsylvania, 2Main Line Health, 3Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA Abstract: Caring for patients with type 2 diabetes mellitus (T2DM) has entered an era with ...
Kamrul Hasan Chowdhury1, Nigel Turner1, Nicholas L. Bentley1, Abhirup Das1, Lindsay E. Wu1, Dulama Richani2, Sonia Bustamante3, Robert B. Gilchrist2, Margaret J. Morris1, Peter R. Shepherd4 & Greg C. Smith1 Type 2 diabetes (T2D) is a ...
This cross-sectional study assesses whether gut microbial taxa play a role in the development of type 2 diabetes using data from 2 Dutch population-based
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality, being twofold to fourfold more common in patients with type 2 diabetes mellitus (T2DM) than in individuals without diabetes. However, despite this decade-old knowledge, the identification of a specific progn...
The reduction of insulin resistance or improvement of insulin sensitivity is the most effective treatment for type 2 diabetes (T2D). We previously reported that Nogo-B receptor (NGBR), encoded by the NUS1 gene, is required for attenuating hepatic lipogenesis by blocking nuclear translocation of ...
We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites, lipids and proteins. Homocitrulline, isoleucine and 2-aminoadipic acid, eight triacylglycerol spec
Type 2 diabetes mellitus (T2DM) is a multifactorial disease resulting from complex interactions between multiple genes and environmental factors1. T2DM is characterized by chronic hyperglycemia, which is known to be caused by insufficient insulin secretion and insulin resistance (IR)2. Oral antidiabetic...