The invention discloses a kit used for detecting genes of type I diabetes of children, which can overcome the limitations of traditional detection methods in principles and operations and detect the hereditary probability that children suffer from diabetes in advance, thereby providing appropriate ...
09 January 2017 Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes Hooi Hooi Ng1,2, Chen Huei Leo1, Darnel Prakoso1,2, Chengxue Qin2, Rebecca H. Ritchie2 & Laura J. Parry1 Serelaxin prevents endothelial...
Lenka Petruzelkova1, Jana Vcelakova1, Stanislava Kolouskova1, Tereza Ulmannova1, Maria Faresjo¨4,5, Ales Neuwirth6, Radek Spisek3, Anna Sediva3, Dominik Filipp6,7 and Zdenek Sumnik1,7 Type 1 diabetes (T1D) is an autoimmune disease characterized by the lack of insulin due to an auto...
To determine whether the prevalence of diabetes has increased between 2001 and 2009, Dabelea and coauthors compared the number of diagnoses among youth
T1, Type 1, Type 1 diabetes– is usually diagnosed in children and young adults but even some young at heart adults are diagnosed. It was previously known as Juvenile Diabetes. In type 1 diabetes, the pancreas stops producing insulin. ...
A recent study using a rat model found significant differences at the time of diabetes onset in the bacterial communities responsible for type 1 diabetes modulation. We hypothesized that type 1 diabetes in humans could also be linked to a specific gut microbiota. Our aim was to quantify and eva...
Abnormal gut microbiota and blood metabolome profiles have been reported both in children and adults with uncomplicated type 1 diabetes as well as in adults with type 1 diabetes and advanced stages of diabetic nephropathy. In this study we aimed to investigate the gut microbiota and a panel of ...
Coded serum samples from healthy controls and newly diagnosed type 1 diabetes patients were analyzed for each autoantibody in the 5-plex ADAP and in each individual RBA using the respective in-house reference standards and cut off levels, respectively, for IAA (Fig. 1), GADA (Fig. 2), IA-...
Initiation of type 1 diabetes (T1D) is marked by the infiltration of plasmacytoid dendritic cells (pDCs) and monocytes in pancreatic islets. Dying beta cells release self-DNA, which forms complexes with antimicrobial peptide, LL37, and its delayed cleara
Diabetes: Bone types respond differently to potential intervention Activation of a key signaling pathway implicated in bone mass maintenance helps boost the strength of spongy internal bone in a mouse model of type 1 diabetes mellitus (T1DM) but also increases the porosity of the outer surface, com...