We developed a deep-learning-based framework, multi-omics variational autoencoders (MOVE), to integrate such data and applied it to a cohort of 789 people with newly diagnosed type 2 diabetes with deep multi-omics phenotyping from the DIRECT consortium. Using in silico perturbations, we ...
Type 2 diabetes Nature Genetics (Nat Genet)ISSN1546-1718(online)ISSN1061-4036(print) Sign up for theNature Briefing: Translational Researchnewsletter — top stories in biotechnology, drug discovery and pharma. Email address Sign up I agree my information will be processed in accordance with theNatu...
Prof Lisa Ng, Executive Director at A*STAR ID Labs, said, "This study sheds light on how TB interacts with other chronic diseases like diabetes. This may prove crucial for the future of health care in Singapore given that the number of diabetics in Singapore is forecasted to increase." Mor...
USRDS 2012 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA (2012) 2. A. Tong, B. Lesmana, D.W. Johnson, et al. The ...
proton pump inhibitors; type 2 diabetes mellitus; upper gastrointestinal disease 1. Introduction Proton pump inhibitors (PPIs) are commonly prescribed to treat peptic acid diseases. To date, PPIs have been among the most frequently prescribed medications [1]; however, PPIs also have problems with ...
Data Set II: The data on 45 patients were available from a private clinic in Tennessee regarding the hemoglobin content in blood being prone to type II diabetes. To see the effect of reducing the hemoglobin content in the blood, a special type of treatment was administered to those patients....
Diabetes gene product. J Biol Chem. 2008, 283: 33685-33697. 10.1074/jbc.M806213200. Article CAS PubMed Central PubMed Google Scholar Wadman IA, Osada H, Grütz GG, Agulnick AD, Westphal H, Forster A, Rabbitts TH: The LIM-only protein Lmo2 is a bridging molecule assembling an ...
ARTICLE doi:10.1038/nature18642 The genetic architecture of type 2 diabetes A list of authors and affiliations appears in the online version of the paper The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual ...
2 Based on statistics from 1999-2002, the standardized prevalence of diagnosed diabetes was 10% in Mexican Americans and 5.2% in whites.3 Although environmental factors such as lifestyle and diet likely explain the majority of this health disparity, it was recently found that genetic variants in...
Type 2 Diabetes Mellitus is a serious metabolic disease that is often associated with vascular complications. There are 1.9 million people living with Diabetes in Ethiopia; diabetes mellitus is found to be the ninth leading cause of death related to its complications. Although the rate of vascular...