Forecasting the changing burden of chronic diseases such as type 2 diabetes in Singapore is vital to plan the resources needed and motivate preventive efforts. This paper describes an individual-level simulation model that uses evidence synthesis from multiple data streams—national statistics, national ...
According to statistics by the International Diabetes Federation (IDF), about 642 million people will have Diabetes by the year 2040 if everything is to remain as it is today. In an attempt to deal with these worrying figures, the World Diabetes Day was established. Observed on November 14th...
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and ...
15). The false-positive rate for these associations is expected to be greater than the false-positive rate for exome-wide significant associations35 and be further influenced by imperfect calibration of association test statistics. If this false-positive rate can be quantified using independent ‘...
To increase power to detect the association of rare variants that clus- ter in individual genes, we deployed gene-level variant aggregation tests15 across the exome sequence data (Methods and Supplementary Table 11). We observed no deviation from the null distribution of association statistics, ...
This study provided evidence for the measurement equivalence of the different language versions of EQ-5D-5L in Singapore.Introduction In outcomes research, measurement equivalence is achieved if a scale generates comparable scores for individuals at the same level of health regardless of the populations...
The body does not produce enough insulin for proper function, or the cells in the body do not react to insulin (insulin resistance). Approximately 90% of all cases of diabetes worldwide are type 2. Measuring the glucose level in blood ...
Department of Epidemiology and Health Statistics, School of Public Health, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, China 9. Department of Endocrine, Nanchong Central Hospital, Nanchong 637000, Sichuan, China 10. Department of Geriatrics, Second People’s Hospital of Chengdu, Chengdu ...
Predicting the course of kidney disease in individuals with both type 1 and type 2 diabetes mellitus (DM) is a significant clinical and policy challenge. In several regions, DM is now the leading cause of end-stage renal disease. The aim of this study to identify both modifiable and non-mo...
Type 2 diabetes and health care costs in Latin America: exploring the need for greater preventive medicine. BMC Med. 12, 136 (2014). Article PubMed PubMed Central Google Scholar Zimmet, P., Alberti, K. G., Magliano, D. J. & Bennett, P. H. Diabetes mellitus statistics on prevalence...