Insulin resistance in type 1 diabetes: what is `double diabetes' and what are the risks? Diabetologia. 2013;56(7):1462-1470.Cleland SJ, Fisher BM, Colhoun HM, Sattar N, Petrie JR. Insulin resistance in type 1 diabetes: what is `double diabetes' and what are the risks? Diabetologia ...
For long the presence of insulin resistance in type 1 diabetes has been questioned. Detailed metabolic analyses revealed 12%-61% and up to 20% lower whole-body (skeletal muscle) and hepatic insulin sensitivity in type 1 diabetes, depending on the population studied. Type 1 diabetes patients fea...
I went to a diabetes Meetup recently where everyone shared how much basal and bolus insulin they used a day. I was blown away at some of the numbers I heard. Some people, even those younger than me and who had had diabetes less time than me, were using more insulin a day than I lo...
If you have type 1, your body doesn't make enough insulin. Withtype 2 diabetes, your body can make insulin but can't use it well. The cells in your muscles, fat, and liver build up what's called insulin resistance. With type 1 diabetes, you need to use man-made insulin every day ...
Insulin resistance in type 1 diabetes: a recipe for double diabetes? The rising level of obesity in the general population is mirrored in patients with type 1 diabetes (T1DM), and this may be further exacerbated by extra weight gain as a result of more intensive insulin regimens employed with...
Obesity is associated with an increased risk of developing insulin resistance and type 2 diabetes. In obese individuals, adipose tissue releases increased amounts of non-esterified fatty acids, glycerol, hormones, pro-inflammatory cytokines and other fac
To evaluate the mechanism of insulin resistance in type 1 diabetes mellitus, we measured insulin sensitivity in vivo and insulin action in adipocytes in vitro. The study groups consisted of 18 insulin-treated type 1 diabetic patients and 14 matched normal subjects. In each subject, insulin-mediated...
Section > Chapter Greenbaum, C.J. Diabetes/Metabolism Research and Reviews 18(3): 192-200 2002 ISSN/ISBN:1520-7552 12112937 10.1002/dmrr.291 010857286 Article emailed within 0-6 h Buy Now for$19.90 Payments are secure & encrypted Abstract...
type 1 diabetesAim Although insulin resistance (IR) is a growing trait among type 1 diabetes (T1D) population, its relationship with atherosclerosis has been scarcely studied. We assessed the association between IR indexes and carotid atherosclerosis in T1D, a population at high cardiovascular ...
Following the seminal discovery of insulin a century ago, treatment of individuals with type 1 diabetes (T1D) has been largely restricted to efforts to monitor and treat metabolic glucose dysregulation. The recent regulatory approval of the first immunot