Details of the fusion protocol and properties of the antibodies are described elsewhere (1). Briefly somatic cell hybridization and growth of hybridomas UL-38 and UL-90 was performed essentially as described by Khler and Milstein (2). As fusion partners PAI-O BALB/c myeloma cells (3), a ...
摘要: An immunoradiometric assay (IRMA) for the determination of human Sex Hormone Binding Globulin (SHBG) in serum is described. This IRMA uses three mouse monoclonal antibodies.关键词: sex hormone binding globulin monoclonal antibodies immunoradiometric assay free androgen index free testosterone ...
This study aimed to characterize two new monoclonal antibodies (mAbs) against HPV L1 protein. Methods The immunocompetence of AE3 and AG7 mAbs for HPV L1 protein was evaluated by Western blot analysis, immunostaining, hemagglutination inhibition assay, and ELISA. The heavy chain variable region (...
Studies of neuroblastoma using two new monoclonal antibodiesStudies of neuroblastoma using two new monoclonal antibodiesdoi:10.1016/0277-5379(91)91522-KZ.G.KadagidzeandN.N.TupitsynandA.Ju.BaryshnikovandI.S.SDOSEuropean Journal of Cancer & Clinical Oncology...
Monoclonal antibodies to two mouse bladder carcinoma antigens. Int J Cancer. 1982 Feb 15; 29 (2):175–180.Hellstrom I, Rollins N, Settle S, et al.: Monoclonal antibodies to two mouse bladder cancer antigens. Int J Cancer 29: 175–180, 1982....
Combines two proven blockbuster monoclonal antibodies: Perjeta® (pertuzumab) and Herceptin® (trastuzumab) in single vial for subcutaneous administration Is also the world’s first subcutaneous therapy for breast cancer that offers faster,...
Two human IgGk monoclonal antibodies (HuMAbs), termed 48-16 and 50-61A, were derived by Epstein-Barr virus transformation of B cells from two HIV-1-infected donors. These HuMAbs recognized discrete, nonoverlapping, and conformational or discontinuous epitopes on the gp120 envelope protein of HI...
In this report we show that two widely-used monoclonal antibodies, TAL-1B5 and DA6.147, which react with the HLA-DRα chain on immunoblots, recognize the C-terminal intracellular tail of this HLA-DR subunit. We demonstrate that both MoAbs react with a synthetic peptide representing the intrac...
Derivation of monoclonal antibodies to two types of human plasminogen activators : L.S. Nielsen1,4, P.A. Andreasen1, J. Zeuthen2,3 and K. Danø1,4. 1Laboratory of Tumor Biology, Institute of Pathology, University of Copenhagen; 2Institute of Human Genetics, University of Aarhus; 3Novo ...
Rudd4,5 & Junzhi Wang1 Two non-human glycan epitopes, galactose-α-1,3-galactose (α-gal) and Neu5Gc-α-2-6-galactose (Neu5Gc) have been shown to be antigenic when attached to Fab oligosaccharides of monoclonal antibodies (mAbs) , while α-gal attached to Fc glycans was not....