It is estimated that two-thirds of all proteins in higher organisms are composed of multiple domains, many of them containing discontinuous folds. However, to date, most in vitro protein folding studies have focused on small, single-domain proteins. As a
10. HA mediates three important processes during the viral life cycle: (1) mediates viral attachment to host cells through interactions of the receptor-binding pocket (RBP) in the head domain with the sialic acid receptors, (2) undergoes dramatic conformational...
The plant cell vacuole has multiple functions, including storage of proteins and maintenance of an acidic pH where proteases will have maximal activity. It has been assumed that these diverse functions occur in the same compartment. Here, we demonstrate that antibodies to two different tonoplast intr...
Retinoids are required for many essential physiological functions, such as cell growth and differentiation, morphogenesis, immunocompetence, and vision (1, 2). Because of their low solubility in aqueous media, these lipids are transported through blood and within cells by proteins that belong to the...
The particle structure of Emiliania huxleyi virus (EhV), an algal infecting member of nucleocytoplasmic large DNA viruses (NCLDVs), contains an outer lipid membrane envelope similar to that found in animal viruses such as African swine fever virus (ASFV)
Zorzano A, Pich S (2006) What is the biological significance of the two mitofusin proteins present in the outer mitochondrial membrane of mammalian cells? IUBMB Life 58: 441-443.Antonio Z,Sara P.What is the Biological Significance of the two Mitofusin Proteins present in the Outer ...
Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such protection is mediated, in large part, by two main B cell memory ‘walls’ — namely, long-lived plasma cells and memory B cells. The cellular and molecular processes that drive the production of lo...
A strategy of on-device phase engineering of two-dimensional materials is proposed, allowing the in situ realization of various lattice phases with distinct stoichiometries and versatile functions. Xiaowei Liu , Junjie Shan & Feng Miao Article | 23 April 2024 Elementary excitations of single-phot...
Two-pore-domain potassium (K2P-) channels conduct outward K+ currents that maintain the resting membrane potential and modulate action potential repolarization. Members of the K2P channel family are widely expressed among different human cell types and o
The genome assemblies were compared to a sequence of reference strain 70–15. By conducting this analysis, we asked the following questions: 1) Do isolate-specific genes and genomic regions exist in these two field isolates? What are their functions and where are they originated? 2) How many...