The Two Membrane Isoforms of Human IgE Assemble into Functionally Distinct B Cell Antigen Receptorsdoi:10.1084/jem.184.6.2197Facundo BatistaShubha AnandGianni PresaniOscar Burrone
of the mass of a cell consist of this semifluid substance ,with is bounded on the outside by the plasma membrane .Organelles are suspended within it ,supported by the filamentous network of the cytoskeleton .dissolved in the cytoplasmic fluid are nutrients ,ions,soluble pro...
Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such protection is mediated, in large part, by two main B cell memory ‘walls’ — namely, long-lived plasma cells and memory B cells. The cellular and molecular processes that drive the production of lo...
It is estimated that two-thirds of all proteins in higher organisms are composed of multiple domains, many of them containing discontinuous folds. However, to date, most in vitro protein folding studies have focused on small, single-domain proteins. As a
The main retinol carriers in the cytosol are the cellular retinol-binding proteins types I and II (CRBP-I and CRBP-II), which exhibit distinct tissue distributions. They play different roles in the maintenance of vitamin A homeostasis and feature a 100-fold difference in retinol affinity whose ...
The particle structure of Emiliania huxleyi virus (EhV), an algal infecting member of nucleocytoplasmic large DNA viruses (NCLDVs), contains an outer lipid membrane envelope similar to that found in animal viruses such as African swine fever virus (ASFV)
Protein phosphorylation, which is critical to the regulation of many cellular processes, regulates the functions of the receptor domains of the TOC components and may impact the selectivity and rate of preprotein import (Demarsy et al., 2014). Some kinases, such as KOC1 at the chloroplast oute...
of neurons and glia in the adult human brain (roughly 85 billion of each type), neurons are responsible for most of the unique functions of the brain. It is the neurons that sense changes in the environment, communicate these changes to other neurons, and command the body’s responses to ...
1b). The patient clinicopathological characteristics are presented in Supplementary Data 1. We obtained single-cell transcriptomes for 144,878 cells after quality control. Thirteen main cell clusters with the expression of known marker genes were identified including epithelial cells, monocytes, ...
A strategy of on-device phase engineering of two-dimensional materials is proposed, allowing the in situ realization of various lattice phases with distinct stoichiometries and versatile functions. Xiaowei Liu , Junjie Shan & Feng Miao Article | 23 April 2024 Elementary excitations of single-phot...