TCRαβ+CD4-CD8α+CD8β- intestinal intraepithelial lymphocytes (CD8αα IELs) are an abundant population of thymus-derived T cells that protect the gut barrier surface. We sought to better define the thymic IEL precursor (IELp) through analysis of its maturation, localization and emigration. ...
The nervous, or neural tissue, is the main tissue component of the nervous system. The nervous tissue occurs 1) centrally (brain and spinal cord), and 2) peripherally (nerves). The neural tissue is composed of two main types of cells- each type ...
What types of immune cells are stimulated when vaccinations are given? Describe innate immunity. What is the major histocompatibility complex (MHC)? How does it contribute to immunity? 1) What are the two classes of lymphocytes, and how are they typically associated with different aspects of adap...
The cohort is part of the B And T Types of Lymphocytes Evaluation in Acute Myocardial Infarction (BATTLE-AMI) study (NCT02428374)52. They had no prior MI and were naive for lipid-lowering treatment. All patients were submitted to pharmacological thrombolysis with tenecteplase in the first 6 h...
However, in the same way that cells originally described as lymphocytes based on their appearance in peripheral blood smears are now known to be comprised of many physiologically distinct subsets, monocytes are morphologically and phenotypically heterogeneous. The term monocyte may therefore describe cells...
Assuming that dsb is the main DNA lesion leading to exchange-type chromosome aberrations (etca), three different mechanisms have to be considered: 1) complex dsb on its own; 2) interaction between two dsb induced by the same primary particle; and 3) interaction between two dsb induced by ...
Strong upregula- tion of IL-12p40, CXCL9, IL-16, and CCL27, mainly produced by activated mononuclear leukocytes including lymphocytes, monocytes, and dendritic cells, are suggestive of a role for mono- nuclear leukocytes in pathogenesis of HFRS. IPA Analysis of Serum Cyto...
ILD were divided into acute (dyspnea within 1 month before diagnosis) or chronic types. ILD was found on chest radiographs in 33 patients (33.3%), and 11 (33.3%) of these were considered acute. The acute group presented with more severe respiratory symptoms, hypoxemia, and poorer lung ...
Two main types of relapses after CAR-T-cell therapy can be discerned, one being the result of downregula- tion or complete loss of the target antigen on the tumor cell surface resulting in an inability of the CAR-T cells to recognize the tumor cells (antigen-negative relapses) and the...
The immune system and lymphatic system work together to combat organisms known and unknown to the body's internal and external environment. Three organs that assist with immunity are the Thymus, Lymph nodes, and Spleen. The thymus secretes hormones, stimu...