This chapter discusses the experimental approaches that have been used to assess the function of two component transcriptional regulation systems following the discovery of a new response regulator or kinase gene. Bacteria possess extensive signal transduction networks that function to regulate transcription....
includingLegionella pneumophila(Lp). Previous work concluded that the stringent response and the sigma factor RpoS are essential for the survival ofLpin water. In the present study, we investigated the role of the LetA/S two-component signal ...
Two-component signal transduction and its role in the expression of bacterial virulence, p. 305–317 - Dzieman, Mekalanos - 1995 () Citation Context ...activates an effector protein, generally a transcriptional regulator, by phosphorylation. 2CRs have been shown to play a crucial role in the ...
transcriptionalactivationdomainofeukaryotes.Thisarchitectureresemblesthatoftypicalbacterialre- sponseregulatorsservingastranscriptionfactors. Keywords:Arabidopsis/Responseregulator/Transcriptionfactor/Two-componentregulatorysystem Two-componentResponseRegulatorsfrom ArabidopsisthalianaContainaPutative ...
This study provides evidence that filamentous have a unique two-component signaling system that is different from that of and is responsible for high-osmolarity adaptation and sensitivity. 展开 关键词: Ascomycota Dioxoles Aminoimidazole Carboxamide Hydantoins Pyrroles Protein Kinases Mitogen-Activated ...
Our previous studies suggested that the essential two-component signal transduction system, YhcSR, regulates the opuCABCD operon at the transcriptional level, and the Pspac-driven opuCABCD partially complements the lethal effects of yhcS antisense RNA expression in Staphylococcus aureus. However, the ...
Two-component signal transduction systems (TCSTs), consisting of a histidine kinase (HK) and a response regulator (RR), represent a major paradigm for signal transduction in prokaryotes. TCSTs play critical roles in sensing and responding to environmenta
Type-A RRs are partially dependent upon transcriptional regulation by type-B RRs [36], [47]. The ARR1-binding element AGATT [34] was found in the promoter of some type-A OsRR genes. Thus, we speculate that the two-component system is conserved between rice and Arabidopsis at the level...
Two- component systems (TCS) are a family of proteins that mediate the adaptation to changing environments by modifying the phosphorylated state of a pair of proteins: a sensor kinase and a response regulator (RR). These systems have been shown to be involved in a variety of bacterial ...
Staphylococcus aureus expresses various cell wall-associated and extracellular virulence factors, coordinately controlled by different two-component signal transduction systems and transcriptional regulators. In this study, we used microarray technology to identify the genes regulated by ArlR. The microarray da...