Thus, there is an urgent need to improve our understanding of the mechanisms of iCCA progression and metastasis so that more advanced diagnostic techniques and novel therapeutic targets can be developed to improve the survival rate of iCCA patients. CircRNAs are generated by back-splicing and form ...
5e) as well as the 100% survival rate during 60 days (Supplementary Fig. 19e). Given that the most potent therapeutic effect was achieved in the LN-TCV + 3L group (Supplementary Fig. 19f), we were also interested in the potential impacts of such multiple irradiations. Considering the...
The participants were categorized into two groups based on the gene expression, and it was revealed that low TMUB1/STT3A levels benefited the overall survival rate in the individuals with breast carcinoma, while HUWE1 is the opposite, consistent with our previous findings in cells. (Fig. 5h ...
Overall survival was calculated from the enrollment date until date of death or last follow-up. The Kaplan-Meier method was used for survival analysis, and a 2-tailed log-rank test was used to determine the significance of the difference. Association of pretreatment ctDNA levels with PFS was ...
In terms of therapeutic benefits in Table 3, even though the inhibition rate of UABD nanomedicines on glioma is more than 90% and the survival time can be prolonged by more than 20%, it is still far from completely cured, not to mention clinical application. Table 3 The specific ...
To determine the response rate and survival of chemotherapy-naive patients with extensive-stage small-cell lung cancer (SCLC) treated with topotecan, and t... JH Schiller,K Kim,P Hutson,... - 《Journal of Clinical Oncology Official Journal of the American Society of Clinical Oncology》 被引量...
We would also like to mention, that despite all treatments decreased tumor volume and increased mice survival, it would be of interest to evaluate the efficacy of achieving tumor regression in other breast cancer models. Finally, we evaluated major organs (brain, lungs, heart, liver, and spleen...
then separate mononuclear cell from heart blood and cultivated them.ELISA and RT-PCR were used to test quantity the expression of IL-4 and IFN-γ.Results: Implanted gastric tumor can be inhibited by Na Ren Man Du La-11 in some degree,Weight-inhibit rate is 44%.IL-4 is lower in ...
3k). The new OFF-ON fixed point in which macrophages lose their dependence on fibroblasts is explained by the inferred circuit in cancer CM (Fig. 3e). The removal rate of macrophages is zero, signifying enhanced survival in the CM. Thus, cancer CM changes all macrophage parameters to allow...
and suppress antitumor immune responses54. IL-8 is also frequently upregulated in the context of cervical cancer and promotes cell migration and proliferation in vitro55. Clinically, high IL-8 titers correspond to advanced-stage cervical neoplasia and poor survival rates56. Our group has demonstrated...