and slow-growth abdominal mass, causing a progressive abdominal distension. Other symptoms, such as nausea and vomiting, respiratory dysfunction, intestinal occlusion, ascites, jaundice, or congestive heart failure, are due to the compression of the tumor mass on surrounding structures and are less co...
The evaluation of a skin tumor is generally similar to the evaluation for any solid tumor. A complete history can be very informative. Careful elucidation of the length of duration, rate of growth, and any clinical signs associated with the tumor may be helpful in differentiating benign from ma...
At follow-up, 81% and 74% of ventricular and atrial tumors, respectively, were minimally symptomatic (New York Heart Association class I/II; P = .13). Patients with atrial and ventricular tumors had a 6% and 0% tumor recurrence rate, respectively (P = .12). Conclusion Surgical resection...
staging MR Imaging Different assessment methods may be utilized to evaluate response of the primary tumor but the most important is the T2-weighted imaging-based magnetic resonance tumor regression grade (mrTRG) (Fig. 4.11), mrTRGs 4 and 5 being associated with worse patient survival [26]....
More than 70% of patients with ovarian cancer are therefore initially diagnosed at an advanced stage, and the 5-year survival rate is only 30%. Ovarian cancer thus presents a serious threat to women’s health [2]. Cancer antigen 125 (CA125) is a clinical ovarian tumor marker, but its ...
inhibitor of MEK1/2 which competitively binds with mitogen-activated protein kinase/extracellular signal-regulated kinases kinase (MEK), inhibits phosphorylation of extracellular signal-regulated kinases (ERKs) and has been reported to block growth factor-mediated cell survival and cell-cycle progression26...
Answer to: BPH is ___, a condition found in men. A. benign prostatic hypertrophy B. benign penile hypercapnia C. blood pressure...
While most physicians recognize that skin is our largest organ, most lay people are unaware of this fact and the important role it plays not only in protection but also in temperature regulation and other activities that are essential to the overall gene
Figure 2. SV inhibited cell survival by promoting cell apoptosis and G0/G1 phase arrest through PPARγ in prostate cells. (A) The relative expression of PPARγ at mRNA levels in BPH-1 and WPMY-1 cells treated by simvastatin at 0 μM, 1 μM, and 5 μM for 48 h. (B) Western bl...
Interestingly, these studies outlined (but did not relate) the absence of metastases and tumor growth amelioration without noticeable side effects, together with the normalization of the heart rate and blood pressure. A few years later, different reports started to show the clinical benefits of ...