Cancer is a complex disease resulting from abnormal cell growth that is induced by a number of genetic and environmental factors. The tumor microenvironment (TME), which involves extracellular matrix, cancer-associated fibroblasts (CAF), tumor-infiltrating immune cells and angiogenesis, plays a critical...
while dormant tumors do not [1]. This highlights the critical role of angiogenesis in tumor progression, as it enables the delivery of oxygen, nutrients, and growth factors to distant organs, as well as the spread of cancerous cells [2]. The process of angiogenesis is regulated by a comple...
In recent years, the tumor microenvironment (TME) has received increasing attention due to its crucial roles in tumor immune suppression, distant metastasis, local resistance and the targeted therapy response [1,2,3,4]. The TME is a highly complicated system mainly composed of tumor cells, infil...
preferential growth of bacteria in tumors5. The first generation of bacterial therapy used natural, live bacteria, inactivated or deactivated, to treat tumors1,2. One successful example is Bacillus Calmette-Guérin (BCG), composed of liveMycobacterium tuberculosis, for the treatment of bladder cancer ...
Leukemia is a cancer that begins in blood-forming tissue, such as the bone marrow, and causes too many abnormal blood cells to be made. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the ...
【佳学基因检测】骨巨细胞瘤(Giant cell tumor of bone)基因检测机构介绍 基因检测机构介绍: 基因检测单位名称:江西省萍乡市基因检测应用中心。其他成熟基因检测项目:疫苗特异性抗体反应降低肿瘤基因检测, 3-甲基戊二酸尿症基因体检 基因检测导读: 骨巨细胞瘤(Giant cell tumor of bone)基因检测结果该怎么看?: ...
of PSA of 0.75 ng/mLin vitro[234]. This LOD is several times better than PSA concentration in human serum associated with a high risk of prostate cancer (from 10 ng/mL) and so-called “grey zone” (4–10 ng/mL) when additional research methods must be used for the diagnosis. But ...
In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a promising immunotherapeutic approach to fight cancers. This approach consists of genetically engineered immune cells expressing a surface receptor, called CAR, that speci
Despite the advancements made in the diagnosis and treatment of cancer, the stages associated with metastasis remain largely incurable and represent the primary cause of cancer-related deaths. The dissemination of cancer is facilitated by circulating tum
The oncogene MYC is dysregulated in a host of human cancers, and as an important point of convergence in multitudinous oncogenic signaling pathways, it plays a crucial role in tumor immune regulation in the tumor immune microenvironment (TIME). Specifica