Some markers are valuable in specific circumstances, such as calcitonin in screening for familial medullary carcinoma of the thyroid. In multiple myeloma, immunoglobulins are useful in determining the tumor mass and response to therapy. In neuroblastoma, catecholamine metabolites are useful primarily in ...
At the protein level, cytometry by time-of-flight mass spectrometry (CyTOF) has emerged as a powerful technique allowing the simultaneous evaluation of up to 40 cell surface or cytoplasmic markers [99]. CyTOF has been successfully applied to study TAMs in lung and brain malignancies [16] among...
Tumor markers may be used for a variety of purposes. However, they are not typically used alone. Depending on the type of cancer, they may be used in conjunction with a tissue biopsy or a bone marrow or blood smear examination, for example, and/or with other tumor markers. They are not...
[Symposium on diagnosis and treatment of cancer. Recent progress. I. Diagnosis. 1. Tumor marker. (1) Main topics on tumor markers]. [Article in Japanese] N Hattori - 《Nihon Naika Gakkai Zasshi the Journal of the Japanese Society of Internal Medicine》 被引量: 0发表: 1987年 Rat Tumor ...
Wisteria floribunda agglutinin-positive mucin 1 is a sensitive biliary marker for human cholangiocarcinoma Cholangiocarcinoma (CC) is an aggressive malignant tumor for which useful markers are not presently available for early and precise diagnosis. The aim of t... A Matsuda,A Kuno,T Kawamoto,......
CD133 is widely used as a marker to identify CRC stem cells and endothelial progenitor cells [73]. It can also be used to predict tumor progression, patient survival and chemoradiotherapy resistance in CRC [74,75] and is one of the most well-characterized markers of cancer stem cells (CSCs...
To complete our studies, we also tested inhibitory markers’ expression on CD4+ T cells from PB and BM and also CD8+ T cells from PB of treated myeloma patients. We found no significant differential expression between naive and treated CD4+ T cells except for CD57, which was also ...
Due to lack of specific markers to define MSCs, their identification was depended on the plastic adhesion property, a panel of surface markers, including CD31, CD34, CD45, CD29, CD90, and CD105, as well as multiple differentiation po- tential. Together with immunosuppressive properties endowed...
The combination of MYC and CAR-T therapy is gradually achieving a precise attack of tumor markers. Some agonizts combined with MYC inhibitors can more fully inhibit the proliferation of tumor cells through different pathways. Although scientists have achieved great results, the clinical results ...
4F, G). To study the effect of IFI35 on CD8+ T cells proliferation in vivo we assayed markers indicative of T cell proliferation. CD8+ T cells from tumors bearing IFI35-overexpressing CT26 cells were more proliferative, based on Ki67 levels (Fig. 4H, I). These results indicated that ...