Not all patients with elevated tumor markers have cancer! (low specificity) Tumor markers are generally not used to screen for or diagnose cancer. However, once cancer has been diagnosed via biopsy, tumor markers can be used to predict therapeutic responses and monitor the effectiveness of canc...
Cancer Markers Diagnosis Almost every cancer marker has been investigated for its suitability as a primary diagnostic test for cancer in symptomatic individuals. However, sufficient false positives and false negatives have been encountered with every marker so far discovered to preclude their use in dist...
US7279294 Apr 3, 2001 Oct 9, 2007 The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services, Nih Using tumor marker proteins such as ceruloplasmin and glutathione perroxidase to diagnose, prognose and detect ovarian cancer...
Tumormarker Auszug Als Tumormarker werden Substanzen bezeichnet, deren Auftreten und Konzentrationsänderung in gewisser Beziehung mit der Entstehung und dem Wachstum von malignen Tumoren eines Individuums stehen. Es wäre von großem Vorteil, wenn es mit Hilfe eines einfachen Labortestes mögl...
Cancer proteomics Tumor marker selection Sample classification Computational methods 1. Introduction In 2015, cancer caused over eight million deaths, making it the second leading cause of death in the world, nearly one-sixth deaths caused by cancer according to the report of the World Health Organiz...
Tumormarker sind nachweisbare oder meßbare Substanzen, die in besonderer Weise auf einen oder mehrere Tumoren hinweisen können, ohne ausschließlich mit ihnen verknüpft zu sein. Einen wesentlichen Teil der Tumormarker stellen die hier behandelten serologischen Tumormarker dar. Ferner zäh...
. Although the tumor fraction distributions of cirrhosis and HCC patients overlapped, the best cut-off value (0.129) of SRFD could still reach a sensitivity of 77.3% at a specificity of 81.0%, which outperformed NNLS and CancerLocator by a large margin. To demonstrate the influence of marker...
A prognostic marker associated with a lower risk of TNBC recurrence could help identify patients who can achieve high cure rates with less intensive therapy. Tumor-infiltrating lymphocyte (TIL) levels are markers of an active antitumor immune response. Patients with early-stage TNBC and high...
pathologischfürdieTransversalbeurteilungfestlegen.Schlüsselwörter:Tumormarker-Sensitivität-Spezifität-prädiktiveWerte-PrävalenzSummary:Incancer diagnosisand thefollow-upofcancer patientsagood cooperationbetweenthephysicianandtheclinicallaboratoryis animportant prerequisite.Fortheselectionofthetumormarkerkit...
Recently AMACR has been reported as an excellent marker as well as MMP.The discovery of prostate cancer fusion genes holds promise both as a marker and as a potential therapeutic target.CONCLUSIONSDespite the PSA test's lack of sensitivity and specificity, it remains the first-line test in ...