E. Bueso- Ramos, "Metastatic tumors in bone marrow: histopathology and advances in the biology of the tumor cells and bone marrowCotta CV,Konoplev S,Medeiros LJ. Metastatic tumors in bone marrow:histopathology and advances in the biology of the tumor cells and bone marrow environment[J]....
May begin in immature cells in the bone marrow and usually affects children and adolescents, age 10-20. The upper leg, arm, pelvis, and ribs are the main locations. Diagnosis and treatment: See your doctor as soon as possible for diagnosis and treatment if you think you might have a bone...
cAMP-elevating agents, such as forskolin, can not only induce cancer cell death, but also directly inhibit cell proliferation in some cancer types. In this review, we summarize current understanding of cAMP signaling in cancer biology and immunology and discuss the basis for its context...
A bone marrow tumor is a type of tumor that originates in the bone marrow, which can be a result of abnormal cell growth within the bone tissue. AI generated definition based on: Imaging of Pain, 2011 About this pageAdd to MendeleySet alert ...
et al. Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils. Proc. Natl. Acad. Sci. USA 112, E566–E575 (2015). Article CAS PubMed PubMed Central Google Scholar Granot, Z. et al. Tumor entrained neutrophils inhibit ...
Detection of disseminated tumor cells (DTCs) in bone marrow is an established negative prognostic factor. We isolated small pools of (~20) EPCAM-positive DTCs from early breast cancer patients for genomic profiling. Genome-wide copy number profiles of DT
BMDM are a set of TAM populations who are recruited from circulating bone marrow-derived macrophages/monocytes (BMDM) [9]. Both subtypes are mononuclear cells that can inhibit CD4 and CD8 lymphocytes. It is known that, in the TME of GBM, TAMs have pro-tumoral roles (M2 TAMs), and their...
Bone marrow-derived cells PGI: Phosphoglucose isomerase AMF: Autocrine motility factor PKM2: Pyruvate kinase isomerase M2 LDHA: Lactate dehydrogenase A FGF: Fibroblast growth factor HGF: Hepatocyte growth factor NK: Natural killer DCs: Dendritic cells MDSC: Myeloid-derived suppressor cells...
FPRs are G protein-coupled receptors (GPCRs) expressed in bone marrow cells and especially on DCs [21]. GPCRs belong to the group of pattern-recognition receptors that can recognize peptides containing N-formylated methionine [21]. There are three human FPRs: FPR1, FPR2, and FPR3. The ...
Xiaoxin was diagnosed with chronic myeloid leukemia, a type of cancer that produces many immature white blood cells and inhibits regular blood production in the bone marrow, at the PKUPH six months ago. Chemotherapy and a bone marrow transplant became urgent for her, but they would directly resul...