The synthesis of a novel cholic acid derivative bearing in the C-3 position a residue of tryptophan linked through an amide bond is herein described. Acidic or basic conditions are needed for the solubilization of the derivative in water. In alkaline solutions the molecule shows a self-...
largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as ...
largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as ...
Formic acid (250 µL 0.8 m) was added after 5 min incubation at room temperature to decompose remaining borohydride and for an acidic pH (pH 4 to 5). Reactions were frozen in liquid nitrogen and subsequently lyophilized. The samples were dissolved in 200 µL methanol, centrifuged (10 ...
degree of cross-linking, eluting the amino acids other than tryptophan with an aqueous solution of an inorganic salt as eluant, and then eluting the tryptophan with a base, if a strongly acidic cation exchange resin is used, or with an acid, if a strongly basic anion exchange resin is ...
Dysregulation of gut microbiota-associated tryptophan metabolism has been observed in patients with multiple sclerosis. However, defining direct mechanistic links between this apparent metabolic rewiring and individual constituents of the gut microbiota
Amino terminus of Plasmodium falciparum acidic basic repeat antigen interacts with the erythrocyte membrane through Band 3 protein Mol. Biochem. Parasitol, 122 (2002), pp. 45-54 View PDFView articleView in ScopusGoogle Scholar 33 X. Li, H. Chen, S.S. Oh, A.H. Chishti A Presenilin-like ...
1,1鈥 - Ethylidenebis-(L-tryptophan) (EBT) is formed from acetaldehyde and Trp under acidic conditions and serves as a marker for EMS-suspicious Trp. 3-(Phenylamino)alanine (PAA) is the only not Trp derived case associated contaminant. Low amounts of PAA (20mg/kg) could be detected ...
The derived cell population consists of 90% to 95% oligodendroglial cells and approximately 5% astrocytes [glial fibrillary acidic protein (GFAP)–positive cells]. The initial adherent cell population served as a source of microglia. Adult Culture Treatment After 1 week in culture, individual wells...
have shown that analogs of (Arg)10 were as efficient as (Arg)10 to enter Jurkat cells when simultaneously modified in positions 2, 5 and 8 by proteinogenic or modified amino acids (Trp and Cys were not tested), except the two analogs with acidic residues: Arg7/Asp3 and Arg7/Glu3, ...