tRNAPyl: Structure, function, and applications. Pyrrolysine is the 22nd proteinogenic amino acid e JM Tharp,A Ehnbom,WR Liu - 《Rna Biology》 被引量: 0发表: 2018年 Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase In addition, a dock...
The identification of novel metabolites and the characterization of their biological functions are major challenges in biology. X-ray crystallography can reveal unanticipated ligands that persist through purification and crystallization. These adventitious protein-ligand complexes provide insights into new activit...
It covers the early days of tRNA research (from 1955-1980) and includes a brief description of the discovery of tRNA, its function in protein synthesis and methods for its purification and sequence analysis.Uttam L RajBhandaryDepartment of BiologyCaroline Koehrer...
A structural element in tRNAs containing a 3-nucleotide sequence complementary to the corresponding codon present in the mRNA. Argonaute proteins A family of proteins that directly bind and mediate the function of regulatory small RNAs. The eukaryotic family is divided into Argonaute proteins and PIWI...
Structure, biosynthesis, and function of queuosine in transfer RNA. Prog. Nucleic Acid Res. Mol. Biol. 28, 49–73 (1983). CAS PubMed Google Scholar Kasai, H., Kuchino, Y., Nihei, K. & Nishimura, S. Distribution of the modified nucleoside Q and its derivatives in animal and plant ...
The structure and function of in vitro transcribed tRNAAsp variants with inserted conformational features characteristic of yeast tRNAPhe, such as the leng... V.,Perret,and,... - 《Journal of Molecular Biology》 被引量: 101发表: 1992年 Identity of tRNA for yeast tyrosyl-tRNA synthetase: tyrosy...
In the chicken mitochondrial genome, the gene for tRNATyr overlaps by one nucleotide with the downstream tRNACys gene, which is located on the same strand... Shin-ichi,Yokobori,and,... - 《Journal of Molecular Biology》 被引量: 122发表: 1997年 Function of a tRNA gene promoter depends on...
tsRNAs can also participate in gene silencing by associating with the PIWI protein (PIWI) and act as piRNA (P-element-induced wimpy testis (PIWI)-interacting small RNAs) [41]. A key function of piRNAs is silencing transposon elements [42]. Ts-101 and ts-53 were reported to correlate with...
Structure-function relationships of glutamine synthetases. As a highly regulated enzyme at the core of nitrogen metabolism, glutamine synthetase has been studied intensively. We review structural and functional stu... D Eisenberg,HS Gill,GMU Pfluegl,... - 《Biochim Biophys Acta》 被引量: 527发表...
In fact, I have already reportedthat Ile-tRNA, synthesized by isoleucyl-tRNA synthetase, is rapidly destroyed by phenylal-anyl-tRNA synthetase, and have suggestedthat the aminoacyl-tRNA synthetases may have a function in addition to synthesis of aminoacyl-tRNAs; that of destruction of misacylated...