What stage is my cancer? Has it spread to lymph nodes (glands near the breast) or other areas? Should I havechemotherapybefore or after surgery? What type of surgery will I need? Will I need radiation treatments? Triple-Negative Breast Cancer Treatment ...
Nishimura R, Arima N: Is triple negative a prognostic factor in breast cancer? Breast Cancer 2008. Toppmeyer D: Locoregional relapse and distant metastasis in conservatively managed triple negative early-stage breast cancer. J Clin Oncol 2006, 24:5652-5657.Reiki Nishimura,Nobuyuki Arima.Is triple...
Management of patients with advanced-stage HER2-positive breast cancer: current evidence and future perspectives Article 08 January 2024 Long-term oncologic outcomes of unselected triple-negative breast cancer patients according to BRCA1/2 mutations Article Open access 30 April 2024 Genomic character...
Triple negative breast cancer (TNBC), which accounts for 15–20% of incident breast cancers, is the only breast cancer (BC) subtype that lacks targeted treatments. Using clinical assays, TNBC is human epidermal growth factor receptor 2 (HER2) negative and has <1% expression of estrogen receptor...
(Herceptin) has been shown to dramatically reduce the risk of the cancer coming back. It‘s standard treatment to give this medication along withchemotherapyafter surgery to people with breast cancer that’s spread to other areas. It can also be used for early-stage breast cancer. But there ...
1Triple Negative Breast cancer (TNBC) 1.1What is Triple Negative Breast Cancer (TNBC) Triple negative breast cancer(TNBC) is a subtype of breast cancer that typically lacks the expression of theoestrogen receptor(ER),progesterone receptor(PR), and does not overexpress the HumanEpidermal Growth Fact...
Triple negative breast cancer (TNBC) is characterized by the lack of estrogen and progesterone receptor expression and lacks HER2 overexpression or gene amplification. It accounts for 10–15% of incident breast cancers and carries the worst prognosis. TN
TNBC, triple-negative breast cancer; BC, breast cancer; BCT, conservative surgery; CHT, chemotherapy; DFS, disease-free survival; LR, local relapse; DR, distant relapse; RT, radiotherapy; OS, overall survival; CMF, cyclophosphamide–methotrexate–5-fluorouracil; BLBC, basal-like breast cancer; PF...
Triple negative breast cancer (TNBC) is an aggressive clinical phenotype characterized by lack of expression (or minimal expression) of estrogen receptor (ER) and progesterone receptor (PR) as well as an absence of human epidermal growth factor receptor-2 (HER2) overexpression. It shows substantial...
Loss of PTEN expression is associated with IGFBP2 expression, younger age, and late stage in triple-negative breast cancer. OBJECTIVES: To investigate the association between PTEN loss and IGFBP2 expression in a series of triple-negative breast cancers and to relate this express... SJR Dean,CM...