Conclusions The positive surgical margin, especially in Stage II and Triple-Negative breast cancer patients negatively impact the patient's evolution, increasing risk of distant metastasis and death.doi:10.1016/j.suronc.2021.101596Rogério Agenor de Araújo...
What stage is my cancer? Has it spread to lymph nodes (glands near the breast) or other areas? Should I havechemotherapybefore or after surgery? What type of surgery will I need? Will I need radiation treatments? Triple-Negative Breast Cancer Treatment ...
(Herceptin) has been shown to dramatically reduce the risk of the cancer coming back. It‘s standard treatment to give this medication along withchemotherapyafter surgery to people with breast cancer that’s spread to other areas. It can also be used for early-stage breast cancer. But there ...
1.1What is Triple Negative Breast Cancer (TNBC) Triple negative breast cancer(TNBC) is a subtype of breast cancer that typically lacks the expression of theoestrogen receptor(ER),progesterone receptor(PR), and does not overexpress the HumanEpidermal Growth Factor Receptor2 (HER2). Consequently, tre...
Triple negative breast cancer is more often responsive to chemotherapy than hormone receptor positive (ER+/PR+) breast cancer. On the other hand, long-term hormonal treatments (tamoxifen, aromatase inhibitors) used for ER+ subtypes are not effective for triple negative breast cancer since estrogen ...
Triple negative breast cancer (TNBC) is characterized by the lack of estrogen and progesterone receptor expression and lacks HER2 overexpression or gene amplification. It accounts for 10–15% of incident breast cancers and carries the worst prognosis. TN
Triple negative breast cancer (TNBC) is characterized by the lack of estrogen and progesterone receptor expression and lacks HER2 overexpression or gene amplification. It accounts for 10–15% of incident breast cancers and carries the worst prognosis. TN
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Management of patients with advanced-stage HER2-positive breast cancer: current evidence and future perspectives Article 08 January 2024 Long-term oncologic outcomes of unselected triple-negative breast cancer patients according to BRCA1/2 mutations Article Open access 30 April 2024 Genomic character...
Immunotherapy has started to transform the treatment of triple-negative breast cancer (TNBC), in part due to the unique immunogenicity of this breast cancer subtype. This review summarizes clinical studies of immunotherapy in advanced and early-stage TNBC. ...