We conclude that SM-164 is a promising therapeutic agent for early stage bone and lung metastasis from triple-negative breast cancer that should be given prior to conventional chemotherapy.doi:10.1038/s41598-020-64018-zWei LeiRong DuanJinbo Li...
Triple-negative breast cancer (TNBC), a subgroup that lacks expression of hormone receptors and HER2, overlaps with basal-like breast cancer (BLBC), a subgroup that expresses cytokeratins and other non-luminal (basal) genes Breast cancers occurring in patients with germline BRCA1 mutations are oft...
Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer (BC) with a poor prognosis. Current treatment options are limited to surgery, adjuvant chemotherapy and radiotherapy; however, a proportion of patients have missed the surgical window at the time of diagnosis. TNBC...
Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model 来自 EBSCO 喜欢 0 阅读量: 50 作者:G Bouchard,H Therriault,S Geha,R Bujold,C Saucier,B Paquette 摘要: The prognosis of triple-negative breast cancer (TNBC) is still difficult to ...
Pingxiao capsule(平消胶囊)inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy OBJECTIVES: To investigate the anticancer effect of Pingxiao capsule(平消胶囊, PXC) on the treatment of breast cancer in vitro and in vivo. METHODS: The in... W Tang...
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer, negatively expresses estrogen receptor, progesterone receptor, and the human epidermal growth factor receptor 2 (HER2). Although chemotherapy is the main form of treatment for patients with TNBC, the effectiveness of ...
Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer (BC) with a poor prognosis. Current treatment options are limited to surgery, adjuvant chemotherapy and radiotherapy; however, a proportion of patients have missed the surgical window at the time of diagnosis. TNBC...
Triple Negative Breast Cancer (TNBC) is a highly heterogeneous subtype of breast cancer that lacks the expression of oestrogen receptors, progesterone receptors and human epidermal growth factor receptor 2. Although TNBC is sensitive to chemotherapy, the
1a). We specifically focus on the paradigm of pyroptosis therapy for triple-negative breast cancer (TNBC), a subtype with highly malignancy and poor prognosis, lacking effective therapeutic targets and treatments19. Pyroptosis has recently been recognized in recent years as a powerful pathway for ...
In breast cancer, nerve presence has been correlated with more invasive disease and worse prognosis, yet the mechanisms by which different types of peripheral nerves drive tumor progression remain poorly understood. In this study, we identified sensory n