标题(英文):Prediction of axillary lymph node metastasis in triple-negative breast cancer by multi-omics analysis and an integrated model 标题(中文):基于多组学分析和整合模型的三阴性乳腺癌腋窝淋巴结转移预测 发表期刊:Ann Transl Med 作者单位:复旦大学附属肿瘤医院等 ...
Triple-negative breast cancer (TNBC) is defined by a lack of expression of both estrogen and progesterone receptor as well as human epidermal growth factor receptor 2. It is characterized by distinct molecular, histological and clinical features including a particularly unfavorable prognosis despite ...
关键词:群体基因组;三阴性乳腺癌(TNBC);淋巴结转移(LNM); 文献介绍 标题(英文):Prediction of axillary lymph node metastasis in triple-negative breast cancer by multi-omics analysis and an integrated model 标题(中文):基于多组学分析和整合模型的三阴性乳腺癌腋窝淋巴结转移预测 发表期刊:Ann Transl Med 作...
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer, negatively expresses estrogen receptor, progesterone receptor, and the human epidermal growth factor receptor 2 (HER2). Although chemotherapy is the main form of treatment for patients with TNBC, the effectiveness of ...
群体基因组文献解读-Prediction of axillary lymph node metastasis in triple-negative breast cancer by multi-omi 毅硕科技 加速创新计算,成就精准数据关键词:群体基因组;三阴性乳腺癌(TNBC);淋巴结转移(LNM); 文献介绍 标题(英文):Prediction of axillary lymph node metastasis in triple-negative breast cancer ...
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer, negatively expresses estrogen receptor, progesterone receptor, and the human epidermal growth factor receptor 2 (HER2). Although chemotherapy is the main form of treatment for patients with TNBC, the effectiveness of ...
Most triple negative breast cancers (TNBCs) are aggressively metastatic with a high degree of intra-tumoral heterogeneity (ITH), but how ITH contributes to metastasis is unclear. Here, clonal dynamics during metastasis were studied in vivo using two patient-derived xenograft (PDX) models established...
Triple‐negative breast cancer (TNBC) is an aggressive form of breast cancer with limited treatment modalities and poor prognosis. Metabolic reprogramming in cancer is considered a hallmark of therapeutic relevance. Here, we report that silibinin disrupts metabolic reprogramming in TNBC cells by ...
Breast cancer brain metastases (BM) affect younger women disproportionally, including those lacking estrogen receptor (ER), progesterone receptor, and HER2 (known as triple-negative breast cancer; TNBC). Previous studies in preclinical models showed that pre-menopausal levels of estradiol (E2) promote...
Triple-negative breast cancer (TNBC) is a distinct breast cancer subtype defined by the absence of estrogen receptor (ER), progesterone receptor (PR) and epidermal growth factor receptor 2 (HER2/neu), and the patients with TNBC are often diagnosed with higher rates of recurrence and metastasis....