Degradation of endogenous proteins and generation of a null-like phenotype in zebrafish using Trim-Away technologyTRIM21, Trim-away, Protein degradation, KnockdownTrim-Away is a recent technique to rapidly deplete a protein from any cell type. Guided by antibodies, TRIM21 selects proteins for ...
Trim-Away is a recently developed technology that exploits off-the-shelf antibodies and the RING E3 ligase and cytosolic antibody receptor TRIM21 to carry out rapid protein depletion. How TRIM21 is catalytically activated upon target engagement, either during its normal immune function or when repurp...
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Trim-Away is a recently developed technology that exploits off-the-shelf antibodies and the RING E3 ligase and cytosolic antibody receptor TRIM21 to carry out rapid protein depletion. How TRIM21 is catalytically activated upon target engagement, either during its normal immune function or when ...
Xinyan Chengrid.59053.3a0000000121679639MOE Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and MedicineUniversity of Science and Technology of China Hefei P.R. ChinaChao Xugrid.59053.3a0000000121679639MOE Key Laboratory for Cellular Dynamics, School of Life ...