此外,5’-tRF-GlyGCC的表达与测量的CRC细胞中ALKBH3的mRNA水平显著正相关(图4d)。 过表达ALKBH3可以增加5’-tRF-GlyGCC的表达(图4 E)。ALKBH3沉默降低了SW480、RKO和PENG-EBV细胞中5’-tRF-GlyGCC的水平(图4f)。一致地,在RKO和SW480细胞中过表达ALKBH3可以增加5’-tRF-GlyGCC的表达(图S4 C),而在HCT1...
The combination of carcinoembryonic antigen (CEA) and carbohydrate antigen 199 (CA199) with 5′-tRF-GlyGCC improves the AUC to 0.926. Consistently, the expression levels of 5′-tRF-GlyGCC in CRC cells and xenograft tissues are significantly greater than that in their corresponding controls. ...
Administration of synthetic tRF-Gly-GCC antagomirs into the right ventricle significantly reduced the infarct volume in both young and aged mice compared to control antagomir-treated groups. Additionally, tRF-Gly-GCC antagomir improved relative apparent diffusion coefficient values in the peri-infarct ...
i-tRF-GlyGCC expression maintained its prognostic value independently of other established prognostic factors, as shown by the multivariate Cox regression analysis. Additionally, survival analysis after TNM stage stratification revealed that higher i-tRF-GlyGCC levels were linked...
Circulatory exosomal tRF-Glu-CTC-005 and tRF-Gly-GCC-002 serve as predictive factors of successful microdissection testicular sperm extraction in patients with nonobstructive azoospermia - ScienceDirectQiang Zhang Ph.D. aZhao Liu M.S. fXiaoxiao Han M.D. g...
tRF-1:30-Gly-GCC-2 may be a novel molecular target for improving the development of atretic follicles in ovarian dysfunction. In conclusion, our study provides a new perspective on the pathogenesis of granulosa cell dysfunction and follicular atresia....
biomedicines Article High Intratumoral i-tRF-GlyGCC Expression Predicts Short-Term Relapse and Poor Overall Survival of Colorectal Cancer Patients, Independent of the TNM Stage Spyridon Christodoulou 1, Katerina Katsaraki 2 , Panteleimon Vassiliu 1, Nikolaos Danias 1, Nikolaos Michalopoulos 1, ...