TREX-2 complexmRNA processingNuclear poreNPCKaryopherinChaperoninNucleoporinThe Three prime repair exonuclease 2 (TREX-2) complex functions as a platform to which many of the components of the nuclear mRNA processing machinery bind, facilitating integration of this phase of the gene expression pathway,...
The TREX-2 complex integrates mRNA nuclear export into the gene expression pathway and is based on aSac3 scaffold to which Thp1, Sem1, Sus1, and Cdc31 bind. TREX-2 also binds the mRNA nuclear export factor, Mex67:Mtr2, through the Sac3 N-terminal region (Sac3N). Here, we ...
The TREX-2 complex localizes to the NPC basket and affects gene-NPC interactions, transcription, and mRNA export. How TREX-2 regulates the gene expression machinery is unknown. Here, we show that TREX-2 interacts with the Mediator complex, an essential regulator of RNA Polymerase (Pol) II. ...
The TREX-2 complex is involved in the step of mRNA export from the nucleus to the cytoplasm. This complex in Drosophila melanogaster consists of four proteins: Xmas-2, PCID2, ENY2, and Sem1p. In our work, we have shown that deletion of the C-terminal sequence of PCID2 leads to a...
Unlike in metazoans, the stepwise biogenesis of microRNAs (miRNAs) in plants occurs within the nucleus. Whether or how the major steps in miRNA biogenesis are coordinated is largely unknown. Here we show that the plant TREX-2 complex promotes multiple st
RNA, MessengerTHO/TREX is a conserved eukaryotic complex formed by the core THO complex plus proteins involved in mRNA metabolism and export such as Sub2... Rondon,G A. - 《Journal of Biological Chemistry》 被引量: 261发表: 2003年
NXF1. Moreover, similar to the case of NXF1 or GANP, loss of TPR led to retention of both upregulated and downregulated mRNA transcripts within the nucleus. Taken together, our data support a unique role of TPR in transcription regulation and mRNA export through the TREX-2 complex. ...
awhich are components of the TREX complex (TREX) (1,2). 哪些是TREX复杂TREX 1,2的 (组分) ()。[translate]
Making it running in optimal way it even more complex.. Our script run good for single instance. 1) Please send the config file for user 1) and user 2) Make sure they have different cores assigned. 2) try to reduce mbuf in both instances to 0.2 (using --mbuf-factor) You should ...
Sultan Iskandar Complex Customs 470 m Meeting Point 490 m Hong Leong Bank @ Jalan Stesen 490 m Johor Bahru Sentral Railway Station 500 m Distances shown are straight-line distances on the map. Actual travel distances may vary. Property policies ...