peptide therapeuticstype 1 diabetes mellitustype 2 diabetes mellitusThis chapter highlights the role of peptides in therapeutic areas such as metabolic disease, where peptides have been well established, as well as in areas where their impact has been minor, but now rapidly expanding. Perhaps more...
Since the introduction of insulin almost a century ago, more than 80 peptide drugs have reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis, multiple sclerosis, HIV infection and chronic pain. In this Perspective, we summarize key trends in peptide drug disco...
Proteins and peptides have a great potential as therapeutic agents; they have higher efficiency and lower toxicity, compared to chemical drugs. However, th
(2) allotopic expression of recoded wild-type mitochondrial genes, including targeted tRNAs and xenotopic expression of cognate genes to compensate for pathogenic mutations; (3) mitochondria targeted-peptides and lipophilic cations for in vivo delivery of antioxidants or other putative therapeutics; and...
PeptideTherapeuticsMarket-GlobalIndustryAnalysis,Size,Share,Growth, TrendsAndForecast,2012–2018 ThePeptidetherapeuticsiscurrentlyofferinganewcommercialpotentialtopharmaceuticals andbiotechnologyindustry.Toexploitthisemergingmarket,largepharmaceuticaland biotechnologicalfirmsareactivelyinvestingindevelopmentofnewerpeptidesforvarious...
The central nervous system (CNS) controls the acquisition and processing of peripheral information to manage the behaviors of organisms. CNS disorders, including CNS injuries, neurodegenerative diseases, and brain tumors, are devastating and can cause li
antimicrobial peptides, small RNAs, and phage therapy have made notable advances in the control of infectious diseases, they are still the third cause of death in the world (Trevisan et al.2017). This review focuses on recent advances in evolution of novel therapeutic agents against drug-resista...
1 The practice of isolating peptides from whole animal tissue continued with the purification of adrenocorticotrophic hormone (ACTH) from livestock pituitary glands to treat a variety of endocrine disorders in patients.2 The utilization of peptides as therapeutics has evolved over time and continues ...
Peptides are referred as amide bonds which are linked with small chains of amino acid monomers. “Peptide therapeutics market” is expected to boost owing to rise in metabolic diseases such as obesity & diabetes and further with growth...
The 224 (56%) non-olfactory GPCRs that are yet to be explored in clinical trials have broad untapped therapeutic potential, particularly in genetic and immune system disorders. Further trends in GPCR drug discovery can be analysed in an interactive resource in the GPCRdb database. ...