By exploring preclinical studies and clinical trials , the chapter underscores the potential of stem cells to repair damaged tissues, modulate the immune response, and, ultimately, alter disease progression . For MS, the chapter examines the role of mesenchymal and hematopoietic stem cells (HSCs) ...
Stimulated by the successful introduction of interferon-β as treatment for relapsing-remitting multiple sclerosis (MS) and based on an improved knowledge of the immunopathology of MS, a vast array of treatment options is currently under investigation for disease course modification. These are targeting...
Multiple Sclerosis Treatments for Relapses While MS affects everyone differently, relapsing-remitting MS causes periods of disease flares. You may recover between these flares (also called remission). Sometimes, all your symptoms go away, but at other times a few symptoms may persist. ...
was supported respectively by a Seed Grant from the Simons Center for the Social Brain, at the Massachusetts Institute of Technology; the International Rett Syndrome Foundation; and by cooperative agreements U01DD000231, U19DD000753, and U01DD001189, funded by the Centers for Disease Control and ...
Here we describe the reasons for this slow progress and outline a number of areas of research that involve a greater reliance on experimental therapeutics utilizing recent advances in neuroscience to better understand disease biology. We exemplify the potential impact of these areas of research focus ...
C Lal,A Khan - 《Copd-journal of Chronic Obstructive Pulmonary Disease》 被引量: 0发表: 2020年 Emerging small-molecule treatments for multiple sclerosis: focus on B cells Multiple sclerosis (MS) is a major cause of disability in young adults. Following an unknown trigger (or triggers), the...
A review of the literature on treating multiple sclerosis (MS) aims to provide physicians with evidence-based information on the latest treatments for this chronic disease. The article, published in CMAJ (Canadian Medical Association Journal) looks at th
Scientists at The University of Nottingham have discovered a molecular mechanism which could bring about the development of new treatments for Multiple Sclerosis (MS) -- a chronic inflammatory disease of the central nervous system.
Chapter 36 – New treatments for multiple sclerosisChapter 36 – New treatments for multiple sclerosisThis chapter presents an overview of new treatments for multiple sclerosis (MS). MS is a disease of the central nervous system (CNS) in which the demyelination and synthesis of immunoglobu...
Time to EDSS6 was similar for the treatment strategies respectively: 14.6 vs 16.4 vs 13.3 years, p=0.13. Conclusions Patients requiring escalation had relatively worse outcomes, and could be identified as having higher disease activity on treatment initiation. This data suggest that initial selection...