Therefore, CP therapy may be an effective method to reduce mortality of severe COVID-19 patients with serious inflammatory response in the absence of specific treatments. In China, CP therapy has been added to the “Diagnosis and Treatment Plan for the Novel Coronavirus Infected Pneumonia (trial ...
For the past decade, cancer treatments have been developed based on RNA interference (RNAi)—a mechanism that effectively “shuts down” malfunctioning genes with small noncoding RNA molecules from the families of microRNAs. LMNA transcripts have a myriad of microRNAs with which they specifically inte...
thyroid hormones and retinoids and plays a major role in lipid and glucose regulation [221]. PPARγ agonists rosiglitazone and pioglitazone have been clinically proven as effective treatments for type 2 diabetes [221]. There is ample evidence...
More- over, if the source of such cells was truly unlimited, it would be possible to provide new treatments from time to time as required if the cells were not self renewing once terminally differentiated. To obtain an unlimited supply of human ES cells it is necessary to establish human ...
The slow spread of treatments supported by empirical evidence and the rapid diffusion of treatments lacking such support play major roles in the lower qual... M Horvitz-Lennon,JM Donohue,ME Domino,... - 《Health Affairs》 被引量: 74发表: 2009年 The Role of Antipsychotic Plasma Levels in th...
Different combinations of these features may naturally cluster into previously undescribed subsets or phenotypes that may have different risks for a poor outcome and may respond differently to treatments. However, efforts to determine such phenotypes have remained limited and have focused primarily on ...
To the best of our knowledge, this is the first study reporting the high throughput potential of NTME combined to GC-MS to characterize the volatomic profile of urine samples without complicated pre-treatments, so could be a versatile tool for future application, providing a good technical advan...
6. Hydroxy/chloroquine: among the suggested treatments for COVID-19 Lack of specific drugs for COVID-19 compels clinicians to depend on an array of treatment strategies which have been used to treat other viral infections such as: (i) convalescent plasma (Casadevall and Pirofski, 2020; Chen...
proteasome-mediated degradation of FoxO1 [123] and by the observation that XBP1 deficiency results in increased levels of FoxO1 [123]. Taken together, the above observations that ER homeostasis is disrupted in HD could be incorporated into future studies aimed at developing novel treatments for HD....
Surgery and chemotherapy are the primary treatments for bladder cancer. However, the current chemotherapy drug protocols are centered on gemcitabine and cisplatin, both of which are costly and have many negative side effects for patients [2, 3]. There are, however, established traditional Chinese ...