- 《Netherlands Journal of Medicine》 被引量: 30发表: 2002年 Challenges in managing profound hypokalaemia: potentially life threatening profound hypokalaemia with metabolic acidosis may not be adequately dealt with by current treatment recommendations. (Papers) Abnormalities of serum potassium are ...
The effect of early diagnosis and treatment in infants with inborn metabolic diseasesBackground: Newborn screening using tandem mass spectrometry (MS/ MS) is an extremely sensitive method of identifying a variety of inborn errors of metabolism mainly aminoacidopathies, organic acidemias and fatty ...
The current standard treatment of neonates with intestinal perforation is surgery. However, the mortality rate after surgical treatment for intestinal perforation is very high for very low birth weight (VLBW) and extremely low birth weight (ELBW) neonates. In this review, conservative treatment of pn...
Metabolic acidosis as defined by a base excess (BE) < − 10 mmol/L (< − 10 mEq/L) or a blood lactate value > 2 mmol/L Exclusion criteria Administration of any systemic antibiotic regimen for > 24 h before randomisation, unless the change is driven by the apparent ...
Hyperventilation to induce hypocapnia and compensate for metabolic acidosis is no longer a primary therapy for pulmonary hypertension, because hypocarbia often results in decreased cerebral perfusion (partial pressure of carbon dioxide [PaCO2] < 30 mm Hg). Prolonged alkalosis has been shown to cause ...
In these severe cases, septic shock, irreversible metabolic acidosis, and bleeding and coagulation dysfunction may occur [11]. At the same time, children with other (i.e., comorbid) diseases (such as congenital heart, lung and airway diseases, malnutrition, and tumors, etc.) are vulnerable ...
After caesarean section maternal blood was drawn in heparinized syringes to transfuse the lambs for correction of hypotension soon after delivery or for blood replacement during the study period. No bicarbonatetherapy was used to correct metabolic acidosiswhen it occurred in the lambs. Natural ...
Maternal oxygen consumption increases incrementally throughout pregnancy, by 20–33% per term gestation, due to increased fetal demands and maternal metabolic processes [59,60]. Mild respiratory alkalosis shifts the oxygen dissociation curve to the left and slightly higher PaO2 levels optimize oxygen ...
Besides, it is noteworthy that two specialized diseases intrahepatic cholestasis of pregnancy (ICP) and Alagille syndrome, whose pathogenesis are correlated to bile acid metabolism and gene mutation common in pregnancy and neonates have certain particularities in the occurrence of cholecythalopathy. Among...
in studies of hypothermia to 33°C in adults, but these were not associated with an adverse outcome [26]. The metabolic rate is reduced during hypothermia and this results in bradycardia and prolonged PR and QT intervals. However, significant arrhythmia has only been reported in adults with ...