The sequelae of cerebral ischemia-reperfusion injury are reduced by administering to the subject a pharmaceutical composition that includes a pharmaceutically acceptable carrier and a therapeutically effective amount of an agent that selectively binds IL-lα.CAMICI, GIOVANNI, GUIDO...
In vivo tracking of the therapeutic stem cells in the host brain after transplantation is essential not only to ensure the safety an... L Lu,Y Wang,M Cao,... - 《Rsc Advances》 被引量: 3发表: 2017年 Exogenous neural stem cell transplantation for cerebral ischemia Cerebral ischemic injury...
Brain is very vulnerable to ischemia, and exhibits various functional impairments in a flow-dependent manner. After onset of ischemia, the following cascade ensues propagating from the ischemic core to the surrounding area; ischemic depolarization, excitatory cellular injury induced by Ca(2+) and glut...
Brain ischemia and neurotransmitter changes: Relevance to migraine pathophysiology and treatment - ScienceDirectCluster headache (CH) can be viewed as a periodic disturbance of bodily adaptive responses to internal or external environmental changes. In the pathophysiology of this disorder many factors must...
Brain injury after stroke requires glutamate receptor activation of neuronal nitric oxide synthase (nNOS), but inhibiting either of these proteins can cause side effects. Now, Dong-Ya Zhu and colleagues show that a drug that blocks the interaction betwee
A rat model of big brain ischemia with the middle brain artery occlusion was used for the study of amantadine sulfate (PK-Merz) effect on the expression of Hsp70 measured with immunohistochemical method and Western blot 12 h and 4 days after surgery. The neuroprotective effect of PK-Merz assoc...
摘要: Medicaments for the treatment or prophylaxis of ischemia- reperfusion injury in myocardial ischemia and cerebral ischemia, characterized in that the medicament contains batroxobin as an effective component.收藏 引用 批量引用 报错 分享 文库来源 其他来源 求助全文 Method for the treatment or ...
Guo X et al (2023) Ischemia Reperfusion Injury Induced Blood Brain Barrier Dysfunction and the involved molecular mechanism. Neurochem Res 48(8):2320–2334 ArticleCASPubMedGoogle Scholar Orellana-Urzúa S et al (2020) Pathophysiology of ischemic Stroke: role of oxidative stress. Curr Pharm Des 26...
(six) brain protective agents: (1) calcium antagonists: to prevent intracellular calcium overload, prevent vasospasm, increase blood flow. The commonly used drugs are nimodipine, nicardipine, flunarizine hydrochloride and cetirizine. (2) cell two phosphorus choline: has the function of stabilizing ...
nominated co-ultraPEALut. The study consisted of two arms. In the first, rats subjected to MCAo and treated with co-ultraPEALut post-ischemia showed reduced edema and brain infract volume, improved neurobehavioral functions, and reduced expression of pro-inflammatory markers and astrocyte markers....