Lyme DiseaseFatal Familial InsomniaPrion Protein GeneOral DoxycyclineNo Abstract available for this article.doi:10.1007/s00415-007-0644-2Prof.Dr. med. Michael StruppDept. of Neurology Ludwig-Maximilians University Klinikum Großhadern Marchioninistr. 15 81377 Munich Germany...
In humans, TSEs are represented by Creutzfeldt Jakob disease (CJD), Gerstmann-Straussler-Scheinker syndrome, Fatal Familial Insomnia and Kuru. In animals, the prominent prion diseases are scrapie of sheep and goats, bovine spongiform encephalopathy (BSE) of cattle and chronic wasting disease (CWD)...
Presumably, this mechanism leads to fibril formation and progressive neurodegeneration in a variety of distinct disorders, including Creutzfeldt–Jakob disease (CJD), fatal familial insomnia, and Gerstmann–Straussler–Scheinker disease. The prion hypothesis was initially viewed as incompatible with the ...
where a series of biochemical reactions occur, ultimately affecting the cell's behavior. The mutations block this process. This discovery may provide a means of genetic diagnosis and a potential target for the therapy of people with familial (and possibly also sporadic) primary pulmonary hypertension...
Four prion diseases known to affect humans are kuru, Creutzfeldt-Jakob Disease (CJD), Gerstmann-Straussler-Scheinker Disease (GSS), and fatal familial insomnia (FFI)). As used herein “prion” includes all forms of prions causing all or any of these diseases or others in any animals used—...
(GSS), fatal familial insomnia(FFI), fatal sporadic insomnia(FSI), scrapie disease, bovine spongiform encephalopathy(BSE), transmissible mink encephalopathy, chronic wasting disease(CWD), and feline spongiform encephalopathy(FSE) comprises: at least one polyanionic compound selected from the group ...
Amongst these are prion diseases such as transmissible spongiform encephalopathies, Alzheimer's disease, Creutzfeldt-Jakob's disease (CJD), the new variant of Creutzfeldt-Jakob's disease (nvCJD), Kuru disease, Gerstmann-Sträusler-Scheinker's syndrome, Fatal Familial Insomnia (FFI) and Scrapies....
Such a cascade of events occurs during the development of Creutzfeldt-Jacob disease (CJD), Kuru, Gerstmann-Straussler-Scheinker Syndrome (GSS), fatal familial insomnia in man, scrapie in sheep and goats, encephalopathy in mink and bovine spongiform encephalopathy in cattle....
Fatal familial insomnia (FFI) PRNP Filariasis Filarioidea superfamily Food poisoning by Clostridium perfringens Clostridium perfringens Free-living amebic infection multiple Fusobacterium infection Fusobacterium species Gas gangrene (Clostridial myonecrosis) usually Clostridium perfringens; other Clostridium species ...
However, they may be responsible for a num- ber of adverse effects, irritability, headache, nervousness, palpitations, insomnia, and less often orofacial dyskinesia, anorexia, nausea, excessive sweating, and psychosis. Toler- ance to amphetamine effect may develop in up to one third of patients ...