Neurosurgical Treatment for Brain Metastases: Clinical Features, Operative Strategies, Recurrence and SurvivalBrain metastases are a frequent complication of cancer arising in up to 15 % of patients with systemic malignancies. Symptoms and findings are highly dependent on the location and size of the ...
Researchers at the Spanish National Cancer Research Center (CNIO) propose a new treatment for brain metastases that respond poorly, or not at all, to immunotherapy, and provide a biomarker to predict in which cases it should be used. Our bodies have a mechanism to destroy anything that attacks...
Brain metastasesChemotherapyBlood–brain barrierCorticosteroidsSupportive careNeuro-oncologyAlthough systemic therapy is the primary therapeutic modality for disseminated cancer, it plays a limited role in the treatment of brain metastases (BM). This review discusses the blood鈥揵rain barrier (BBB), ...
Necessary treatment of brain metastases in poor﹑erformance status patients: for all, for no one, or for whom?brain metastasesperformance statusprognosisstereotactic radiosurgeryThe optimum treatment of brain metastases (BRM) in people with poor performance status remains to be ascertained. We aimed ...
An artificial intelligence (AI)-based tool can predict local failure (LF) afterradiation therapyforbrain metastases(BM) using the baseline treatment-planning MRI, a new study suggests. The tool was 83% accurate in predicting treatment failure, while oncologists accurately predict treatment failure abo...
2017. Treatment trends for patients with brain metastases: Does practice reflect the data? Cancer 123:2274-2282.Sandler KA, Shaverdian N, Cook RR, et al. Treatment trends for patients with brain metastases: does practice reflect the data? Cancer 2017;123:2274e82....
Brainlab is excited to introduce a comprehensive solution for the treatment of multiple brain metastases at the ESTRO Annual Meeting. Come experience the combination of the revolutionary Automatic Brain Metastases Planning software with the well-established ExacTrac® IGRT system, offering a precise and...
Abemaciclib has been shown preclinically to cross the blood-brain barrier, providing rationale for testing this agent in pts with BM. Furthermore, as previously presented, levels of abemaciclib similar to plasma were detected in resected BM in a subset of pts with HR+, HER2- MBC in this ...
Anita Mahajan, MD, professor, The University of Texas MD Anderson Cancer Center, discusses a recent study into the role of stereotactic radiosurgery in treating brain metastases.Recent Videos Related Content Advancing Neoadjuvant Therapy for HER2+ Breast Cancer Through ctDNA Monitoring Jordyn Sava ...
Eligible patients had histologically confirmed MM to the brain, and no prior radiotherapy or radiosurgery for brain metastases. Previously untreated patients received temozolomide at 200 mg/m(2)/d x 5 days; previously treated patients received 150 mg/m(2)/d x 5 days every 28 days. Treatment ...