Soffietti R, Abacioglu U, Baumert B et al. Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro- Oncology (EANO). Neuro-oncology 2017; 19(2):162-174.Soffietti R, Abacioglu U, Baumert B, Combs SE, Kinhult S, Kros JM, et...
Brain metastases Diagnosis and treatment Nanomedicine Blood-brain barrier Blood-tumor barrier Drug resistance 1. Epidemiology Brain metastases represent a frequent complication of cancers and are more common than primary brain tumors [1]. Each year in the United States, ∼170,000 patients are diagnos...
Introduction: Thirty per cent of cancer patients develop brain metastases, with multiple combination or sequential treatment modalities available, to treat systemic or central nervous system (CNS) disease. Most patients experience toxicities as a result of these treatments, of which cognitive impairment ...
2017. Treatment trends for patients with brain metastases: Does practice reflect the data? Cancer 123:2274-2282.Sandler KA, Shaverdian N, Cook RR, et al. Treatment trends for patients with brain metastases: does practice reflect the data? Cancer 2017;123:2274e82....
The incidence of brain metastases has markedly increased in the past 20 years owing to progress in the treatment of malignant solid tumours, earlier diagnosis by MRI and an ageing population. Although local therapies remain the mainstay of treatment for
Treatment options for these women remain limited, particularly at the time of central nervous system (CNS) relapse following completion of initial CNS-directed therapy. Historically, prior studies have broadly examined systemic treatments for breast cancer brain metastases with mixed, but overall ...
NSCLC brain metastases treatment with immune checkpoint inhibitor monotherapy The discovery of ICI has vastly improved the OS of patients in comparison to traditional therapies and drastically changed treatment guidelines. ICI has cemented its place in metastatic NSCLC according to the National Comprehensive...
Modern treatment of brain metastases has dramatically changed the expected prognosis. Traditionally, the prognosis has been considered very poor, and patients were referred to palliative treatment because of their terminal stage; however, new prognostic indexes have been proposed to evaluate these patients...
Brain metastases represent a major source of morbidity in patients with cancer.Methods. Treatment outcomes were analyzed retrospectively in 214... Ehud,Arbit,D M.,... - 《Cancer》 被引量: 210发表: 1995年 Impact of breast surgery on survival in patients with distant metastases at initial ...
Brain metastases (BM) affect clinical management and prognosis but limited resources exist to estimate BM risk in newly diagnosed cancer patients. Additionally, guidelines for brain MRI screening are limited. We aimed to develop and validate models to pr