Brain metastases represent a common and devastating complication of cancer. With advances in surgery, radiology, and medical and radiation oncology, the number of treatment options have greatly increased. In addition, the prognosis for patients can vary widely depending on factors such as the number ...
The incidence of brain metastases has markedly increased in the past 20 years owing to progress in the treatment of malignant solid tumours, earlier diagnosis by MRI and an ageing population. Although local therapies remain the mainstay of treatment for many patients with brain metastases, a growin...
the management of brain metastases has historically relied on local therapies including surgery and radiation. However, novel targeted and immune therapies that improve overall outcomes in lung cancer have demonstrated effective intracranial activity. As a result, the management of brain metastases in ...
Management of Brain Metastases: Surgery, Radiation, or Both? A significant number of cancer patients will develop intracranial metastases. In general, treatment of these lesions uses a combination of surgery and radi... Toral,R.,Patel,... - 《Hematology/oncology Clinics of North America》 被引...
Non-small cell lung cancer (NSCLC) is associated with an increased risk for the development of brain metastases and the prognosis until recently has been poor except for some patients' subgroups and depending on the disease-specific GPA prognostic factors [4].For patients receiving only best ...
Management of recurrent brain metastasis after radiosurgery. Stereotactic radiosurgery (SRS) has become a first-line treatment option for brain metastases, both as a boost following whole-brain radiation therapy (WBR... AL Stockham,JH Suh,ST Chao,... - Karger Publishers 被引量: 19发表: 2012年...
Therapeutic management of brain metastasis This review focuses on the management of brain metastases. The four main modes of therapy are discussed: whole brain radiation therapy (WBRT), surgery, rad... EC Kaal,CG Niël,CJ Vecht - 《Lancet Neurology》 被引量: 320发表: 2005年 Temozolomide, th...
The management of brain metastases. Brain metastases are neoplasms that originate in tissues outside the brain and then spread secondarily to the brain. Metastases to the brain are the most c... RA Patchell - 《Cancer Treatment Reviews》 被引量: 1385发表: 2003年 Management of brain metastases...
Advances in neurosurgery and the development of stereotactic radiosurgery have expanded treatment options available for patients with brain metastases. However, despite several randomized clinical trials and multiple uncontrolled studies, there is not a uniform consensus on the best treatment strategy for all...
Background: 2040% of patients with malignant tumors have one or more brain metastases in the course of their illness. Brain metastases are the first manifestation of cancer in 510%. Manifestations such as intracranial hypertension or focal neurologic deficits are seen in over 80% of patients with...