Excessive daytime sleepiness (EDS) is a hallmark symptom of narcolepsy. The second major symptom, cataplexy, is present only in a subgroup of patients with narcolepsy. Fortunately, existing pharmacologi
Diagnosing and Treating Excessive Daytime Sleepiness in Narcolepsy or Obstructive Sleep ApneaKotagal, SureshJournal of Managed Care Medicine
Sleep apnea and excessive daytime somnolence induced by vagal nerve stimulation. Neurology 61: 1126–1129. Huang Y, Sommer M, Thickbroom GW, Hamada M, Pascual-Leone A, Paulus W et al (2009). Consensus: new methodologies for brain stimulation. Brain Stimulat 2: 2–13. Hummel FC, Celnik...
we can find dryness of the nose and throat which can evolve into soreness.Nasal congestionand runny nose are also frequent side effects, as well as irritation of the eyes and skin of the face. Other less frequent symptoms are abdominalbloatingand, oddly enough, exc...
• Excessive focus on sleep, heightened anx- iety about sleep • Difficulty falling asleep in bed at desired time, but not during monotonous activi- ties when not intending to sleep • More able to fall asleep when away from home ...
is excessive daytime sleepiness. OSAS is now recognized as a leading cause of daytime sleepiness and has been implicated as an important risk factor for such problems as motor vehicle accidents. Other related symptoms include intellectual impairment, memory loss, personality disturbances. and impotence....
The methods of present invention include treating excessive daytime sleepiness in patients diagnosed with Prader-Willi syndrome. In another embodiment, the present invention relates to methods of treating NES in patients comprising administering to the patient, in need of such treatment, a therapeutically...
SUBSTANCE: invention refers to medicine, and aims at treating excessive daytime sleepiness (EDS). It involves introducing a therapeutically effective amount of an enantiomer (R) betaaminobenzopropyl urethane or an enantiomer compound in which the enantiomer (R) prevails. EFFECT: method allows ...
Introduction: Narcolepsy is a rare sleep disorder characterized by excessive daytime sleepiness, cataplexy, disturbed nocturnal sleep, hypnagogic hallucinations, and sleep paralysis. Pitolisant is a first-in-class drug acting on histamine 3 receptors and indicated for the treatment of narcolepsy. This ...
Conversely, 12 randomised trials in which excessive daytime sleepiness was generally an exclusion criterion showed no reduction in cardiovascular event rates. The SERVE-HF trial showed an increase in mortality with use of minute ventilation-triggered adaptive servo-ventilation for CSA in patients with ...