Table 1. Integral outer membrane proteins of E. coli K-12. ClassNamea (UniProt)UniProt IDFunction (UniProt)Alternative functions Classical β-barrels 8-Stranded Empty Cell OmpA P0A910 Anchor between peptidoglycan and outer membrane Empty Cell OmpW P0A915 Uncharacterized Receptor for colicin S4 Emp...
MembraneproteinTemperaturesensingTransmembranesignalingLipidinteractionCell membranes are composed of a lipid bilayer containing proteins that cross and/or interact with lipids on either side of the two leaflets. The basic structure of cell membranes is this bilayer, composed of two opposing lipid ...
Cell Membranes, Cell Biology, glycerophospholipid, membrane, transmembrane proteinsScitable
Cell membrane spanning proteins contain a luminal/extracellular domain, a transmembrane region and a cytosolic domain. In a type I transmembrane protein the N‐terminus is the extracellular/luminal part of the protein, whereas the C‐terminus comprises the cytosolic region of the membrane protein. Tu...
Interaction of hepatitis C virus proteins with host cell membranes and lipids JeanDubuisson, ...DariusMoradpour, inTrends in Cell Biology, 2002 Cleavage of the NS2 N-terminus from p7 is thought to occur through a signal peptidase in the ER[61]. But the membrane association of NS2 can occur...
Liquid-liquid phase separation of proteins occurs on both surfaces of cellular membranes during diverse physiological processes. In vitro reconstitution could provide insight into the mechanisms underlying these events. However, most existing reconstitut
Transmembrane signaling proteins play a crucial role in the transduction of information across cell membranes. One function of regulated intramembrane proteolysis (RIP) is the release of signaling factors from transmembrane proteins. To study the ro
Here, we report that when the complete modular unit encoded precisely by exons 9−12 is expressed in Escherichia coli as glycine 404 through serine 589, i.e., as [G404−N432]NBF1 or as ΔF508[G404−N432]NBF1, the resultant proteins target the cytoplasmic membrane. Significantly, ...
A potential difference is registered only when the microelectrode is inserted into the cell; no potential is registered if the microelectrode is in the bathing fluid. FIGURE 11-20 Structure of a resting K+ channel from the bacterium Streptomyces lividans. All K+ channel proteins are tetramers ...
Transmembrane proteins have important roles in cells, as they are involved in energy production, signal transduction, cell-cell interaction, cell-cell communication and more. In human cells, they are frequently targets for pharmaceuticals; therefore, kno