The researchers evaluated the translation in real time through distinguishing the size of the residual hairpin. Furthermore, they also indicated that pause lengths depend on the secondary structure of mRNA wherein the applied force from the optical tweezers modifies the secondary structure of the mRNA...
Method for Monitoring Gene Expression of Translation and Integral/Secretory Protein Synthesis by Magnetic Resonance Spectroscopy (MRS) Disclosed is a method for monitoring change in gene expression of translation and integral/secretory protein synthesis in a sample comprising measuring the... JF Norfray ...
The elevation of expression levels for secreted glycoproteins by gene amplification in mammalian cells shows a saturation behavior at high levels of gene amplification. At high expression levels a drop in the secretion efficiency for the recombinant protein occurs (Schröder and Friedl, 1997), coincid...
of cyclin B mRNAs of Xenopus laevis to work out how different arrangements of the 3'UTR elements hexanucleotide AAUAAA site and the cytoplasmic polyadenylation element (CPE) determine whether an messenger RNA is repressed or activated, and whether it is activated early or late in the cell cycle...
Tunable translation-level CRISPR interference by dCas13 and engineered gRNA in bacteria It’s difficult to precisely modulate translation-level gene expression using CRISPR-dCas13 due to the lack of detailed characterization of the system. Here, the authors fill the knowledge gap and develop a synt...
This process is called gene expression, and the genetic information is used within a cell to produce the proteins needed for the cell to function. The process of making RNA from DNA is transcription, a process of RNA biosynthesis. It is the first step in gene expression, and it is a ...
Translation not only defines gene expression, but it is the sine qua non without which modern (protein-based) cells would not have come into existence. Yet from the start, the problem of translation has been misunderstood--a reflection of the molecular perspective that dominated Biology of the ...
In these integrated studies, serial analyses of gene expression and DNA microarrays have been used to quantify the transcriptome, while proteome analysis has... HC Jane - 《Briefings in Functional Genomics & Proteomics》 被引量: 278发表: 2004年 Integrated transcriptome and proteome data: The challe...
Regulation of gene expression through translational control is a fundamental mechanism implicated in many biological processes ranging from memory formation to innate immunity and whose dysregulation contributes to human diseases. Genome wide analyses of translational control strive to identify differential tran...
4) gene expression 基因表达 1. Alterations of gene expression profiles in lungs of rats following sulfur dioxide inhalation; 二氧化硫吸入致大鼠肺组织基因表达谱改变 2. Effect of heroin on gene expression of nucleotides catabolism in C6 glioma cell; 海洛因对C6细胞嘌呤核苷酸分解代谢基因表达的影响 ...