These effects are probably caused by interactions between the peptide and translation factors, rRNAs or the tunnel through which it is transported to the surface of the ribosome [154], and it is likely that similar mechanisms exist in eukaryotes. Ribosomal pause sites not ascribed to secondary ...
This volume represents the proceedings of the 24th Mos bach Colloquium on "Regulation of Transcription and Trans lation in Eukaryotes" which was held April 26-28, 1973, in Mosbach, Germany, under the auspices of the Gesellschaft fiir Biologische Chemie. To the three of us (H. KERSTEN, P. ...
GCN1-interacting proteins other than GCN2 remain relatively unexplored in higher eukaryotes. By contrast, a conserved C-terminal region of yeast Gcn1, which includes R2259, has been shown to mediate interactions with the RWD domains of yeast Gcn2, Yih1, and Gir2.20,50 Mutation of Gcn1 R...
In the case of photosynthetic eukaryotes, a previous transcriptome analysis suggested a model in which the G1/S transition is regulated by the light and time-dependent transcription of G1/S regulators4. However, the mechanism of the circadian gating of cell division and the nature of the ...
The eukaryotic translation initiation factor 5A (eIF5A), a small acidic protein found in eukaryotes and archea but not in eubacteria, was proposed to function during translation initiation as a nucleo-cytoplasmic shuttle for a sub- set of mRNAs necessary during cell cycle progression from G1 to...
Regulation of translation initiation in eukaryotes: mechanisms and biological targets Cell, 136 (2009), pp. 731-745 View PDFView articleView in ScopusGoogle Scholar Starke et al., 2015 S. Starke, I. Jost, O. Rossbach, T. Schneider, S. Schreiner, L.H. Hung, A. Bindereif Exon circulariz...
For eukaryotes: • Met-tRNAmet is used for both initiation and elongation. Prokaryotic Met-tRNAmet • Prokaryotic Met-tRNAmet can be formylated to fMet-tRNAimet. Met-tRNAmet + N10-formyl tetrahydrofolate (四氢叶酸) formyl Transferase 甲酰转移酶 ...
Figure 1. The general process of translation in eukaryotes. A typical eukaryotic mRNA is represented. The cap structure (m7G), the open reading frame (light blue box) and the poly(A) tail are depicted. During Initiation, most eukaryotic mRNAs are translated by the cap-dependent mechanism, ...
Family of filamentous proteins (tektin-1, 418aa; tektin-2, 430aa, tektin-3, 490aa; tektin-4, 435aa; tektin-5, 485aa) associated with outer-doublet microtubules in ciliary and flagellar axonemes in all eukaryotes except higher plants. The filaments are 2 nm in diameter and ...
The interplay between the RNA decay and translation machinery in eukaryotes 2018, Cold Spring Harbor Perspectives in Biology Y14 governs p53 expression and modulates DNA damage sensitivity 2017, Scientific Reports View all citing articles on Scopus * This work was supported by Grant MOST 102-2311-B...