Methods. To compare the efficacy of CHr and TSAT as an indicator for treatment of iron deficiency, we conducted a single-center, open-label, prospective, randomized, controlled trial at the Kidney Center in Shinraku-en Hospital of 197 Japanese patients on chronic hemodialysis. After 4 weeks ...
Transferrin saturation ratio and risk of total and cardiovascular mortality in the general population.Background: The transferrin saturation (TSAT) ratio is a commonly used indicator of iron deficiency and iron overload in clinical practice but precise relationships with total and cardiovascular mortality...
Expression of Duodenal Iron Transporter Proteins in Diabetic Patients with and without Iron Deficiency Anemia Serum transferrin receptor (sTfR) is another marker which is a truncated form of the transferrin receptor present on erythroblasts in bone marrow and many other cells in the body. Stages of...
Transferrin is a blood plasma protein for iron delivery that, in humans, is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important ...
and to associate iron status with long-term prognosis.Methods and resultsSerum concentrations of ferritin, transferrin saturation (Tsat), soluble transferrin ... EA Jankowska,J Malyszko,H Ardehali,... - 《European Heart Journal》 被引量: 315发表: 2012年 Diagnosis of iron deficiency in chronic...
Increased plasma transferrin level is related to diseases such as iron deficiency anemia while decrease plasma transferrin is related to iron overload diseases and protein malnutrition. Uses Transferrin (Holo) is the primary iron binding and cell delivery molecule present in serum. Serum-free cell ...
Introduction: Iron deficiency (ID) is often present (32% - 65%) in patients with heart failure (HF). Oral iron absorption in patients with HF is generallypoor. This is the reason why oral treatment is not recommended. Aim: To test whether oral iron succinate significantly increases iron ...
Transferrin saturation (TSAT) is a reliable marker of iron status. According to National Kidney Foundation - Dialysis Outcomes Quality Initiative (NKF-DOQI) guidelines, a TSAT < 20% indicates iron deficiency, whereas a TSAT > 50% may indicate iron overload in hemodialysis (HD) patients.1'2...
Conclusions: Low TSAT was a significant independent risk factor for all-cause mortality in a cohort of Japanese patients on MHD. The findings of this study suggest that the adverse clinical outcomes in patients with low TSAT can be partly attributed to infection-related iron deficiency....
Low SI or low Sat without anemia is often equated with latent iron deficiency. Several studies have suggested that the SI and Sat may be lower in children than in adults. However, in the absence of systematically derived standards, adult values are commonly used. We studied a healthy group ...