(3)接下来,计算每个年龄段内每个细胞和细胞类型之间的欧式距离([欧氏距离](https://www.cnblogs.com/xregan/p/11006912.html)),该欧氏距离用作每个细胞转录噪声的一种量度,此外,将每只young or old小鼠样本得到的欧氏距离取平均值,and calculated the transcriptional noise ratio between young and old mice. (...
For example, when the gain ratio θ/(θ + a) is small, each model predicts Poisson-like RNA count distributions, which are not very sensitive to the value of κ. To illustrate the conditions under which parameter recovery appears to be possible, we performed an in silico parameter ...
the analytic expression of signal-to-noise ratio is obtained.The effects of the additive noise intensity α,the multiplicative noise intensity D and the amplitude of input periodic signal A on the signal-to-noise ratio are analysed by numerical calculation.It is found that the existence of a ...
However, a lack of change within individual DEG targets of fish without signs of BSD could also indicate low signal-to-noise ratios in genomic targets, or a temporal effect from exposure that was not captured at the time of sample. A time-course assessment of these types of DEG targets ...
be combined with photoactivation (paFCS) to fine-tune the number of fluorescent molecules detected by selectively activating only a desired fraction of the molecules [32], thereby enhancing the signal-to-noise ratio and making it suitable for systems with high fluorescence background. Integrating SPI...
they must be designed to respond specifically to the desired target chemical with minimal cross-reactivity, no leaky expression in the OFF-state, and sufficient output when activated (ON-state) to give an adequately large signal-to-noise ratio, as otherwise the construction of complex, higher-ord...
(We did not use the last converted read to determine the front because this measure would be too sensitive to noise in the data.) Elongation rates were calculated by fitting a linear model on the front positions of Pol II in 0, 15, 30 and 45 min in the first 100 kb of each ...
Before the behavioral test, mice were habituated in the behavior room in the presence of background white noise for at least 30 min. At day 1, a mouse was habituated to the apparatus for free exploration for 20 min (pre-training, also as open field test). At day 2, the mouse ...
In the negative control, half of the cells come from reporter− embryos and express no GFP (green dots) and half express high levels of GFP, causing a shift in the ratio of green to yellow fluorescence (red dots). The reduced GFP population shown in blue represents only noise/scatter ...
3a). The significance level that removes nodes from the network with low signal-to-noise ratio can be set to a desired false discovery rate. It can be shown that removal of noisy nodes imposes a sparsity constraint on the inference problem (Online Methods). The different steps required to ...