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2.1 Transcription of ProkaryotesInitiation phase: RNA-pol recognizes the promoter and starts the transcription. Elongation phase: the RNA strand is continuously growing. Termination phase: the RNA-pol s 13、tops synthesis and the nascent RNA is separated from the DNA template. a. InitiationRNA-pol...
Although DNA replication is a fundamental aspect of biology, it is not known what determines where DNA replication starts and stops in the human genome. We directly identified and quantitatively compared sites of replication initiation and termination in untransformed human cells. We found that ...
Transcription-coupled DNA repair removes bulky DNA lesions from the genome1,2 and protects cells against ultraviolet (UV) irradiation3. Transcription-coupled DNA repair begins when RNA polymerase II (Pol II) stalls at a DNA lesion and recruits the C
30、d DNA and a dinucleotide that represents the first two bases in the RNA product. Abortive initiation describes a process in which RNA polymerase starts transcription but terminates before it has left the promoter. It then reinitiates. Several cycles may occur before the elongation stage begins...
The process that leads to successful fruit formation starts at early stages of floral meristem development and follows a series of chronologically successive events. In this work we report the functional characterization of the class-II homeodomain leucine zipper (HD-ZIP) JAIBA (JAB) gene. Mutant ...
Transcription initiationis the phase during which the first nucleotides in theRNAchain are synthesized. It is a multistep process that starts when theRNAPholoenzyme binds to the DNAtemplateand ends when the corepolymeraseescapes from the promoter after the synthesis of approximately the first nine nu...
Therefore, it was suggested that the translation of the UL53 open reading frame (ORF) starts at an internal initiation codon that is located 55 codons downstream of the putative one. A hybrid selection experiment was performed in which the UL53-specific mRNA was selected from BSC-I cells ...
Cleavage enzymes of ATAC-seq and DNase-seq. Sequence motif relative to aligned read starts after cleavage with Tn5 and DNase I enzymes on naked DNA ATAC-seq (a) and DNase-seq (b) experiments. Position 1 corresponds to the start position of the ATAC/DNase-seq read. The size of the motif...