In subject area: Biochemistry, Genetics and Molecular Biology The general transcription factor TFIID is composed of the TATA binding protein (TBP) and thirteen TBP associated factors (Tafs) which recognize gene promoters in a activator dependant way. ...
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The termination model describes this form in terms of the rate of RNA chain initiation ( V i), the rate of polymerase propagation and chain elongation ( V p), and the length of the DNA template ( D). The duration of the lag phase is shown to be inversely proportional to V p and ...
Play videos and type your transcripts in the same window.Insert timecodesanywhere in your transcript, then click on a timecode to jump to that point in the movie. Quickly insertfrequently used textwith a single keystroke using custom snippets. Freelytype anywhere in the transcript, just like a...
Chromosomal architecture is known to influence gene expression, yet its role in controlling cell fate remains poorly understood. Reprogramming of somatic cells into pluripotent stem cells (PSCs) by the transcription factors (TFs) OCT4, SOX2, KLF4 and MYC offers an opportunity to address this questi...
Through single-cell transcriptomics, ATAC-Seq and ChIP-Seq profiling, we expose a key role for NFIB and NFIX in governing super-enhancer maintenance of the key hair follicle SC-specific TF genes. When NFIB and NFIX are genetically removed, the stemness epigenetic landscape is lost. Super-...
but rather as simple conceptual guides to understand the forces at play. Thus, the models neglect such details as whether each residue in the binding domain of the TF recognizes one or more DNA bases, as well as issues of DNA malleability, non-specific amino-acid base contacts, etc. The ...
SNPs identified as diQTLs and those identified as tiQTLs show significant overlap in terms of the tTREs they are located within. 52.1% of tTREs associated with a diQTL also contain an associated tiQTL, comprising 6.4% of tTREs with tiQTLs. Focusing only on primary diQTL SNPs, defined as...
The workflow is very simple: Gather some audio Click record. Works when recording for real or when playing the track in a DAW. Or drop an audio file on the plugin. (.wav, .aiff, .flac, .mp3 and .ogg (vorbis) supported) The MIDI transcription instantly appears in the piano roll secti...